Results 11 to 20 of about 238 (118)

Structure of the full-length TRPV2 channel by cryo-EM [PDF]

open access: yesNature Communications, 2016
Transient receptor potential (TRP) proteins are Ca2+-permeable cation channels activated by a range of chemical and physical stimuli. Here the authors describe a cryo-EM structure of the full-length TRPV2 channel that provides insight into the regulation
Kevin W. Huynh   +6 more
doaj   +2 more sources

A REVIEW ON ROLE OF TRPV CATION CHANNELS

open access: yesJournal of Biomedical and Pharmaceutical Research, 2021
The mammalian branch of the Transient Receptor Potential (TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC (‘Canonical’), TRPV (‘Vanilloid’), TRPM (‘Melastatin’), TRPP (‘Polycystin’), TRPML (‘Mucolipin’) and the TRPA (‘Ankyrin’) group.
Deep Sharma, Rekha Rana, Kiran Thakur
openaire   +2 more sources

Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19

open access: yesFrontiers in Medicine, 2021
The battle against the new coronavirus that continues to kill millions of people will be still long. Novel strategies are demanded to control infection, mitigate symptoms and treatment of COVID-19. This is even more imperative given the long sequels that
Filippo Liviero   +3 more
doaj   +1 more source

TRP channels: Role in neurodegenerative diseases and therapeutic targets

open access: yesHeliyon, 2023
TRP (Transient receptor potential) channels are integral membrane proteins consisting of a superfamily of cation channels that allow permeability of both monovalent and divalent cations. TRP channels are subdivided into six subfamilies: TRPC, TRPV, TRPM,
Mashoque Ahmad Rather   +6 more
doaj   +1 more source

Effect of Aging, Gender and Sensory Stimulation of TRPV1 Receptors with Capsaicin on Spontaneous Swallowing Frequency in Patients with Oropharyngeal Dysphagia: A Proof-of-Concept Study

open access: yesDiagnostics, 2021
Spontaneous swallowing contributes to airway protection and depends on the activation of brainstem reflex circuits in the central pattern generator (CPG).
Weslania Nascimento   +6 more
doaj   +1 more source

Vascular Dysfunction in Diabetes and Obesity: Focus on TRP Channels

open access: yesFrontiers in Physiology, 2021
Transient receptor potential (TRP) superfamily consists of a diverse group of non-selective cation channels that has a wide tissue distribution and is involved in many physiological processes including sensory perception, secretion of hormones ...
Raiana dos Anjos Moraes   +4 more
doaj   +1 more source

Neonatal Bladder Irritation Is Associated With Vanilloid Receptor TRPV1 Expression in Adult Rats [PDF]

open access: yesInternational Neurourology Journal, 2018
Purpose To evaluate whether mild chemical irritation of the bladder in neonatal rats is associated with persistent vanilloid receptor transient receptor potential vanilloid subfamily 1 (TRPV1) activity in adult rats.
Jee Soo Park   +4 more
doaj   +1 more source

Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes. [PDF]

open access: yes, 2017
Ion channels play important roles in chondrocyte mechanotransduction. The transient receptor potential vanilloid (TRPV) subfamily of ion channels consists of six members.
Hdud, IM   +4 more
core   +2 more sources

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel

open access: yesNature Communications, 2016
TRPV are cation channels activated by physical and chemical stimuli. Here the authors show that nicotinamide is a soluble, endogenous agonist for orthologous TRPV channels fromC.
Awani Upadhyay   +10 more
doaj   +1 more source

Transient receptor potential cation channel vanilloid (TRPV) 4 in ventilator‐induced lung injury (VILI)

open access: yesThe FASEB Journal, 2013
Study objective Ca 2+ entry via TRPV4 has been implicated in stretch‐induced barrier failure in isolated lungs. Here, we assessed the relevance of TRPV4 in VILI in vivo , and probed for the contribution
Laura Michalick   +3 more
openaire   +1 more source

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