Results 31 to 40 of about 1,008,370 (159)

Neonatal Bladder Irritation Is Associated With Vanilloid Receptor TRPV1 Expression in Adult Rats [PDF]

open access: yesInternational Neurourology Journal, 2018
Purpose To evaluate whether mild chemical irritation of the bladder in neonatal rats is associated with persistent vanilloid receptor transient receptor potential vanilloid subfamily 1 (TRPV1) activity in adult rats.
Jee Soo Park   +4 more
doaj   +1 more source

Transient receptor potential cation channel vanilloid (TRPV) 4 in ventilator‐induced lung injury (VILI)

open access: yesThe FASEB Journal, 2013
Study objective Ca 2+ entry via TRPV4 has been implicated in stretch‐induced barrier failure in isolated lungs. Here, we assessed the relevance of TRPV4 in VILI in vivo , and probed for the contribution
Laura Michalick   +3 more
openaire   +1 more source

Structure of the full-length TRPV2 channel by cryo-EM

open access: yesNature Communications, 2016
Transient receptor potential (TRP) proteins are Ca2+-permeable cation channels activated by a range of chemical and physical stimuli. Here the authors describe a cryo-EM structure of the full-length TRPV2 channel that provides insight into the regulation
Kevin W. Huynh   +6 more
doaj   +1 more source

Vanilloid transient receptor potential cation channels: An overview [PDF]

open access: yes, 2008
The mammalian branch of the Transient Receptor Potential ( TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC ('Canonical'), TRPV ('Vanilloid'), TRPM ('Melastatin'), TRPP ('Polycystin ...
Vennekens, Rudi   +2 more
core   +1 more source

TRP Channels in Angiogenesis and Other Endothelial Functions

open access: yesFrontiers in Physiology, 2018
Angiogenesis is the growth of blood vessels mediated by proliferation, migration, and spatial organization of endothelial cells. This mechanism is regulated by a balance between stimulatory and inhibitory factors.
Tarik Smani   +7 more
doaj   +1 more source

Inhibition of diacylglycerol–sensitive TRPC channels by synthetic and natural steroids [PDF]

open access: yes, 2012
TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca2+ signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition have ...
Kleemann, Heinz-Werner   +35 more
core   +2 more sources

Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna [PDF]

open access: yes, 2011
[cat] Aquesta tesi es centra en la genètica de la migranya. La migranya comuna és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap.
Carreño, Oriel
core   +6 more sources

TRP Channels Role in Pain Associated With Neurodegenerative Diseases

open access: yesFrontiers in Neuroscience, 2020
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and excitable cells from diverse tissues, including heart, lung, and brain.
Milena Duitama   +5 more
doaj   +1 more source

Generators of Pressure-Evoked Currents in Vertebrate Outer Retinal Neurons

open access: yesCells, 2021
(1) Background: High-tension glaucoma damages the peripheral vision dominated by rods. How mechanosensitive channels (MSCs) in the outer retina mediate pressure responses is unclear. (2) Methods: Immunocytochemistry, patch clamp, and channel fluorescence
Ji-Jie Pang, Fan Gao, Samuel M. Wu
doaj   +1 more source

TRPV4 is the temperature-sensitive ion channel of human sperm

open access: yeseLife, 2018
Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium.
Nadine Mundt   +2 more
doaj   +1 more source

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