Results 41 to 50 of about 1,008,370 (159)

Role of Transient Receptor Potential Vanilloid Channels (TRPV) in Cancer: Narrative Review [PDF]

, 2022
Cancer is the leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. It leads cancer to being a global problem. Cancer can modify calcium signaling networks by altering the expression and function of cation channels, pumps ...
HAIKAL, Muhamad Adly
core  

Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes. [PDF]

, 2017
Ion channels play important roles in chondrocyte mechanotransduction. The transient receptor potential vanilloid (TRPV) subfamily of ion channels consists of six members.
Hdud, IM, Loughna, P, Mobasheri, A, El-Shafei, AA, Barrett-Jolley, R   +4 more
core   +3 more sources

TRPV channels in tumor growth and progression

, 2011
Transient receptor potential (TRP) channels affect several physiological and pathological processes. In particular, TRP channels have been recently involved in the triggering of enhanced proliferation, aberrant differentiation, and resistance to ...
AMANTINI, Consuelo, FARFARIELLO, Valerio, SANTONI, Giorgio   +2 more
core   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Functional expression of TRPV4 channels in human collecting duct cells : implications for secondary hypertension in diabetic nephropathy [PDF]

, 2012
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Hills, Claire E., Bland, Rosemary, Squires, Paul E.   +2 more
core   +1 more source

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

Laser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo, Sarassunta Ucci, Anna Aliberti, Patrizio Vaiano, Alessia La Rocca, Francesca Angelone, Silvia Pascarella, Pellegrino Lippiello, Maria Concetta Miniaci, Giuseppe Prisco, Michela Russo, Francesco Amato, Deyanira Contartese, Milena Fini, Gianluca Giavaresi, Lucia Martini, Francesco Rosa, Cosimo Gentile, Emanuele Gruppioni, Armando Ricciardi, Andrea Cusano   +20 more
wiley   +1 more source

The expression of TRPV channels, prostaglandin E2 and pro-inflammatory cytokines during behavioural fever in fish [PDF]

, 2018
A fever, or increased body temperature, is a symptom of inflammation, which is a complex defence reaction of the organism to pathogenic infections. After pathogens enter the body, immune cells secrete a number of agents, the functions of which stimulate ...
Diego Crespo, Arriagada, Gabriel, Daniela Vergara, Sonia Rey, Luis Mercado, Boltana, Sebastian, Nataly Sanhueza, Andrea Donoso, Byron Morales-Lange, MacKenzie, Simon, Simon Mackenzie, Sanhueza, Nataly, Lluis Tort, Aguilar, Andrea, Morales-Lange, Byron, Gabriel Arriagada, Donoso, Andrea, Crespo, Diego, Rey, Sonia, Andrea Aguilar, Mercado, Luis, Tort, Lluis, Sebastian Boltana, Vergara, Daniela   +23 more
core   +1 more source

Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains

BMC Genomics, 2006
Background The purpose of this work was to study the gene expression of transient receptor potential (TRP) channels in the mouse. The application of a standardized and quantitative technique, TaqMan RT-PCR, should give information about the pattern and ...
Krüger Jana, Bisping Frederike, Kunert-Keil Christiane, Brinkmeier Heinrich   +3 more
doaj   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

TRPV channels activation induces cell death in Human Pancreatic Ductal Adenocarcinoma cell lines

, 2022
Introduction Pancreatic Ductal Adenocarcinoma is one of the most aggressive and lethal malignancy. The main therapeutic strategy is surgical resection followed by adjuvant chemotherapy, but only 10-20-% of patients have a resectable form, while if it is
G. Santoni, M. B. Morelli, O. Marinelli, C. Amantini, C. Aguzzi, F. Maggi, M. Nabissi, L. Zeppa   +7 more
core   +1 more source