Results 61 to 70 of about 22,398 (184)
Histone modifications in Trypanosoma brucei [PDF]
Molecular and Biochemical Parasitology, 2007 Several biological processes in Trypanosoma brucei are affected by chromatin structure, including gene expression, cell cycle regulation, and life-cycle stage differentiation. In Saccharomyces cerevisiae and other organisms, chromatin structure is dependent upon posttranslational modifications of histones, which have been mapped in detail. The tails of
Veena, Mandava +5 more
openaire +2 more sources
Protein Science, Volume 35, Issue 7, July 2026.Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone +15 more
wiley +1 more source
Identification of Trypanosoma brucei gambiense in naturally infected dogs in Nigeria
Parasites & Vectors, 2019 Background Animal trypanosomosis is endemic in Nigeria, while the human disease caused by Trypanosoma brucei gambiense is rarely reported nowadays after efforts to bring it under control in the 20th century.
Paschal Ugochukwu Umeakuana +3 more
doaj +1 more source
Mass spectrometry proteomics for studying mitostasis
Protein Science, Volume 35, Issue 7, July 2026.Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma +5 more
wiley +1 more source
Edelfosine (ET-18-OCH3) a Promising Alkylphospholipid against Resistant Trichomonas vaginalis
Proceedings, 2017 Edelfosine (ET-18-OCH3) is an alkylphospholipid with an analogous structure to miltefosine. Both molecules are active against kinetoplastids (Leishmania spp., Trypanosoma cruzi and Trypanosoma brucei). [...]
Alexandra Ibáñez-Escribano +3 more
doaj +1 more source
Structure of thioredoxin from Trypanosoma brucei brucei
FEBS Letters, 2003 The three‐dimensional structure of thioredoxin from Trypanosoma brucei brucei has been determined at 1.4 Å resolution. The overall structure is more similar to that of human thioredoxin than to any other thioredoxin structure. The most striking difference to other thioredoxins is the absence of a buried carboxylate behind the active site cysteines ...
Friemann, Rosmarie +5 more
openaire +2 more sources
Journal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin +2 more
wiley +1 more source
Réponse du poulet nigérian local ( Gallus domesticus) aux trypanosomes
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988 La réponse du poulet nigérian local aux souches de Trypanosoma brucei 8/18 et T. vivax Y58 a été recherchée. Le poulet local utilisé dans cette étude était sensible à T. brucei mais réfractaire à T. vivax (Y58) (une souche adaptée aux rongeurs).
O.A. Dina, R.O.A. Arowolo
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Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon. [PDF]
PLoS Neglected Tropical Diseases, 2019 BACKGROUND:Human African Trypanosomiasis (HAT) is a neglected tropical disease caused by infections due to Trypanosoma brucei subspecies. In addition to the well-established environmental and behavioural risks of becoming infected, there is evidence for ...
Elvis Ofon +10 more
doaj +1 more source