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Antioxidant defense in Trypanosoma brucei brucei
2003Two genera of protozoa belonging to the order Kinetoplastida, Trypanosoma and Leishmania, are pathogenic for mammals and cause widespread diseases of man and his livestock in developing countries. Their successful survival depends mainly on evading the hostsï immune system by penetrating and multiplying within the cells. As intracellular pathogens they
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Lipid composition of bloodstream forms of Trypanosoma brucei brucei
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986The qualitative and quantitative lipid composition of bloodstream forms of Trypanosoma brucei brucei S42 was compared with that of rat plasma and erythrocytes. The concentrations of lipid-bound phosphate and lipid-bound sialic acid in the trypanosomes were markedly higher than those of the rodent tissues.
M, Carroll, P, McCrorie
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cAMP signalling in Trypanosoma brucei
International Journal for Parasitology, 2001Cyclic AMP was the first second messenger to be identified. After five decades of research, much is currently known about its biological functions and clinical implications. Several components of the cAMP signalling pathways, such as the G-protein coupled receptors and the phosphodiesterases, have become sensitive and specific drug targets for a host ...
T, Seebeck +5 more
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Putrescine activated S-adenosylmethionine decarboxylase from Trypanosoma brucei brucei
Molecular and Cellular Biochemistry, 1992Trypanosoma brucei brucei contained a S-adenosyl-L-methionine decarboxylase (AdoMetDC) strongly activated by putrescine. The enzyme was also activated to a lesser extent by cadaverine and 1,3-diaminopropane. Spermidine and spermine had no effect on basal activity of the enzyme.
B L, Tekwani, C J, Bacchi, A E, Pegg
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Protein isoprenylation in Trypanosoma brucei brucei
Biochemical Society Transactions, 1996H, Field +3 more
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Uptake of α-difluoromethylornithine by Trypanosoma brucei brucei
Biochemical Pharmacology, 1986A J, Bitonti +3 more
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Silencing of the thioredoxin gene in Trypanosoma brucei brucei
Molecular and Biochemical Parasitology, 2002Armin, Schmidt +2 more
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