Results 91 to 100 of about 18,054 (201)

Cholesterol transport and beyond: Illuminating the versatile functions of HDL apolipoproteins through structural insights and functional implications

BioFactors, Volume 50, Issue 5, Page 922-956, September/October 2024.
High‐density lipoproteins are versatile lipoprotein nanoparticles that have pleotropic functions in regulating lipid metabolism, innate immunity, and protection of cardiovascular system. They comprise of several proteins among which 15 apolipoproteins are the major proteins, with diverse functions.
Aishwarya Sudam Bhale, Olivier Meilhac, Christian Lefebvre d'Hellencourt, Mookambeswaran A. Vijayalakshmi, Krishnan Venkataraman   +4 more
wiley   +1 more source

Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal

PLoS Neglected Tropical Diseases, 2012
El resultado final de la infección por Trypanosoma brucei gambiense, el principal agente de la enfermedad del sueño, siempre se ha considerado invariablemente fatal. Si bien los informes escasos y antiguos han mencionado casos de autocuración en pacientes no tratados, estos estudios sufrieron la falta de herramientas de diagnóstico precisas disponibles
Vincent Jamonneau, Hamidou Ilboudo, Jacques Kaboré, Dramane Kaba, Mathurin Koffi, Philippe Solano, André Garcia, David Courtin, Claude Laveissière, Lingué Kouakou, Philippe Büscher, Bruno Bucheton   +11 more
openaire   +6 more sources

Trypanosomes and gut microbiota interactions in triatomine bugs and tsetse flies: A vectorial perspective

Medical and Veterinary Entomology, Volume 38, Issue 3, Page 253-268, September 2024.
Trypanosoma sp. presence modulates or has zero effect on gut microbiota composition. Microbiota presence modulates or has zero effect on Trypanosoma sp. growth. Vector biology of triatomine bugs and tsetse flies influences their gut microbiota composition.
Zeph Nelson Omondi, Ayşe Caner, Suha Kenan Arserim   +2 more
wiley   +1 more source

How are Trypanosoma brucei receptors protected from host antibody‐mediated attack?

BioEssays, Volume 46, Issue 7, July 2024.
Trypanosoma brucei acquires host macromolecular nutrients such as transferrin (Tf) and haptoglobin‐hemoglobin (Hp‐Hb) for their survival. This process is mediated by specific receptors embedded within VSG coat, which is constantly at risk of being recognized by host anti‐receptor antibodies.
Sourav Banerjee, Nicola Minshall, Helena Webb, Mark Carrington   +3 more
wiley   +1 more source

Human African Trypanosomiasis in Emigrant Returning to China from Gabon, 2017

Emerging Infectious Diseases, 2018
Human African trypanosomiasis is endemic to parts of sub-Saharan Africa and should be considered in the differential diagnosis of patients who have visited or lived in Africa.
Xinyu Wang, Qiaoling Ruan, Wen-Hong Zhang, Jianfei Gu, Yiyi Qian, Muxin Chen, Qin Liu, Qing Lu, Wenhong Zhang   +8 more
doaj   +1 more source

Novel quinoline derivatives with broad‐spectrum antiprotozoal activities

Archiv der Pharmazie, Volume 357, Issue 6, June 2024.
Several quinoline derivatives incorporating arylnitro and aminochalcone moieties were synthesized and evaluated in vitro against a broad panel of trypanosomatid protozoan parasites. Compounds 2c, 2d, and 4i displayed submicromolar activity against Trypanosoma brucei rhodesiense, with high selectivity relative to human lung fibroblasts and mouse primary
Carla B. Hartman, Phelelisiwe S. Dube, Lesetja J. Legoabe, Natascha Van Pelt, An Matheeussen, Guy Caljon, Richard M. Beteck   +6 more
wiley   +1 more source

Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum

BMC Genomics, 2008
Background African trypanosomes (including Trypanosoma brucei) are unicellular parasites which multiply in the mammalian bloodstream. T. brucei has about twenty telomeric bloodstream form Variant Surface Glycoprotein (VSG) expression sites (BESs), of ...
Becker Marion, Kurioka Ayako, Taylor Jesse E, Young Rosanna, Louis Edward J, Rudenko Gloria   +5 more
doaj   +1 more source

Enzyme variation in Trypanosoma brucei spp. I. Evidence for the sub-speciation of Trypanosoma brucei gambiense

Parasitology, 1984
SummaryThree groups of stocks of Trypanosoma brucei ssp, defined by the criteria of host, human serum resistance and place of isolation as T. b. gambiense, T. b. brucei (Nigeria) and T. b. brucei/rhodesiense (non-gambiense, Uganda) were screened for electrophoretic variation at 20 enzyme loci.
Eldirdiri A. Babiker, D. Le Ray, Andrew Tait   +2 more
openaire   +3 more sources

Treatment of mucocutaneous leishmaniasis – A systematic review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 6, Page 763-773, June 2024.
Summary Mucocutaneous leishmaniasis is a severe infectious disease, predominantly endemic in Central and South America and is characterized by granulomatous, destructive mucosal lesions in the oral, nasal, and pharyngeal cavities. It is caused by protozoa of the genus Leishmania spp. transmitted to humans by sandflies.
Theresa Fischer, Marcellus Fischer, Sibylle Schliemann, Peter Elsner   +3 more
wiley   +1 more source

African Trypanosomiasis Gambiense, Italy

Emerging Infectious Diseases, 2005
African trypanosomiasis caused by Trypanosoma brucei gambiense has not been reported in Italy. We report 2 cases diagnosed in the summer of 2004. Theses cases suggest an increased risk for expatriates working in trypanosomiasis-endemic countries.
Zeno Bisoffi, Anna Beltrame, Geraldo Monteiro, Alessandra Arzese, Stefania Marocco, Giada Rorato, Mariella Anselmi, Pierluigi Viale   +7 more
doaj   +1 more source