Results 31 to 40 of about 18,366 (207)

Ethical Considerations for Global Health Decision-Making: Justice-Enhanced Cost-Effectiveness Analysis of New Technologies for Trypanosoma brucei gambiense. [PDF]

Public Health Ethics, 2018
We sought to assess formally the extent to which different control and elimination strategies for human African trypanosomiasis Trypanosoma brucei gambiense (Gambiense HAT) would exacerbate or alleviate experiences of societal disadvantage that ...
Merritt MW, Sutherland CS, Tediosi F.
europepmc   +2 more sources

Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum [PDF]

BMC Genomics, 2008
Background African trypanosomes (including Trypanosoma brucei) are unicellular parasites which multiply in the mammalian bloodstream. T. brucei has about twenty telomeric bloodstream form Variant Surface Glycoprotein (VSG) expression sites (BESs), of ...
Becker Marion, Kurioka Ayako, Taylor Jesse E, Young Rosanna, Louis Edward J, Rudenko Gloria   +5 more
doaj   +2 more sources

Genetic Diversity in the Diminazene Resistance-Associated P2 Adenosine Transporter-1 (AT-1) Gene of Trypanosoma evansi [PDF]

Animals
Trypanosomes are parasitic protozoa that cause severe diseases in humans and animals. The most important species of Trypanosmes include Trypanosoma evansi and Trypanosoma brucei gambiense.
Shoaib Ashraf, Ghulam Yasein, Qasim Ali, Kiran Afshan, Martha Betson, Neil Sargison, Umer Chaudhry   +6 more
doaj   +2 more sources

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: Hypothalamic Peptidergic Sleep and Wake-Regulatory Neurons [PDF]

Frontiers in Neuroanatomy, 2018
Neuron populations of the lateral hypothalamus which synthesize the orexin (OX)/hypocretin or melanin-concentrating hormone (MCH) peptides play crucial, reciprocal roles in regulating wake stability and sleep.
Claudia Laperchia, Yuan-Zhong Xu, Dieudonné Mumba Ngoyi, Tiziana Cotrufo, Marina Bentivoglio, Marina Bentivoglio   +5 more
doaj   +2 more sources

Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study.

Lancet Glob Health, 2021
Kande Betu Ku Mesu V, Mutombo Kalonji W, Bardonneau C, Valverde Mordt O, Ngolo Tete D, Blesson S, Simon F, Delhomme S, Bernhard S, Mahenzi Mbembo H, Mpia Moke C, Lumeya Vuvu S, Mudji E'kitiak J, Akwaso Masa F, Mukendi Ilunga M, Mpoyi Muamba Nzambi D, Mayala Malu T, Kapongo Tshilumbwa S, Botalema Bolengi F, Nkieri Matsho M, Lumbala C, Scherrer B, Strub-Wourgaft N, Tarral A.   +23 more
europepmc   +2 more sources

Characterization of recombinant Trypanosoma brucei gambiense Translationally Controlled Tumor Protein (rTbgTCTP) and its interaction with Glossina midgut bacteria. [PDF]

Gut Microbes, 2017
In humans, sleeping sickness (i.e. Human African Trypanosomiasis) is caused by the protozoan parasites Trypanosoma brucei gambiense (Tbg) in West and Central Africa, and T. b. rhodesiense in East Africa.
Bossard G, Bartoli M, Fardeau ML, Holzmuller P, Ollivier B, Geiger A.   +5 more
europepmc   +2 more sources

Trypanosoma brucei gambiense [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Molecular Evidence of a Trypanosoma brucei gambiense Sylvatic Cycle in the Human African Trypanosomiasis Foci of Equatorial Guinea

Frontiers in Microbiology, 2015
Gambiense trypanosomiasis is considered an anthroponotic disease. Consequently, control programs are generally aimed at stopping transmission of Trypanosoma brucei gambiense (T. b. gambiense) by detecting and treating human cases.
Carlos eCordon-Obras, Yasmin eFermin Rodriguez, Amalia eFernandez-Martinez, Jorge eCano, Nicolas eNdong-Mabale, Policarpo eNcogo-Ada, Pedro eNdongo Asumu, Pilar eAparicio, Miguel eNavarro, Agustin eBenito, Jean-Mathieu eBart, Jean-Mathieu eBart   +11 more
doaj   +2 more sources

The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected. [PDF]

Parasite Epidemiol Control, 2019
Mehlitz D, Molyneux DH.
europepmc   +2 more sources

VSGs Expressed during Natural T. b. gambiense Infection Exhibit Extensive Sequence Divergence and a Subspecies-Specific Bias towards Type B N-Terminal Domains

mBio, 2022
Trypanosoma brucei gambiense is the primary causative agent of human African trypanosomiasis (HAT), a vector-borne disease endemic to West and Central Africa.
Jaime So, Sarah Sudlow, Abeer Sayeed, Tanner Grudda, Stijn Deborggraeve, Dieudonné Mumba Ngoyi, Didier Kashiama Desamber, Bill Wickstead, Veerle Lejon, Monica R. Mugnier   +9 more
doaj   +1 more source