Results 61 to 70 of about 18,054 (201)

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis.

PLoS Neglected Tropical Diseases, 2010
BackgroundTrypanosoma brucei gambiense is the causative agent of chronic Human African Trypanosomiasis or sleeping sickness, a disease endemic across often poor and rural areas of Western and Central Africa.
Andrew P Jackson, Mandy Sanders, Andrew Berry, Jacqueline McQuillan, Martin A Aslett, Michael A Quail, Bridget Chukualim, Paul Capewell, Annette MacLeod, Sara E Melville, Wendy Gibson, J David Barry, Matthew Berriman, Christiane Hertz-Fowler   +13 more
doaj   +1 more source

Enzyme polymorphism and the identity of Trypanosoma brucei gambiense

Parasitology, 1987
SUMMARYThirty-two isolates from man in known areas of Gambian trypanosomiasis, in the Sudan, Kenya, Zaire, Nigeria, Ivory Coast, Burkina Faso, Liberia and Senegal, were examined by isoenzyme electrophoresis of 11 enzymes. Comparisons were also made with our previously published results on 23 other stocks of similar origins, which had been examined in ...
D. Mehlitz, U. Zillmann, Catherine M. Scott, Wendy Gibson, D. G. Godfrey   +4 more
openaire   +3 more sources

G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area.

Journal of Infection in Developing Countries
INTRODUCTION Apolipoprotein L1 (APOL1) risk variants (G1, G2) are known to enhance the protective ability against human African trypanosomiasis (HAT), in addition to their role in kidney and cardiovascular disease.
D. Mupepe, M. Wameso, Hippolyte N. Situakibanza, P. Ekulu, J. R. Makulo, J. M. N. Kayembe, A. Nkoy, Raggue ZM Mvibudulu, L. P. Van den Heuvel, Elena Levtchenko, K. Karume, Victoire A. Bikoumou, N. Buila, Benjamin M. Longo, Dieudonné N Mumba, Jean-René M'buyamba-Kabangu   +15 more
semanticscholar   +1 more source

Measure of Molecular Diversity within the Trypanosoma brucei Subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as Revealed by Genotypic Characterization

Experimental Parasitology, 2001
We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP).
Agbo, E.C., Majiwa, P.A.O., Classsen, E.J.H.M., Roos, M.H.   +3 more
openaire   +4 more sources

Identification of Trypanosoma brucei gambiense and T. b. rhodesiense in vectors using multiplexed high-resolution melt analysis

bioRxiv, 2020
Background Human African Trypanosomiasis (HAT) is a potentially fatal parasitic infection caused by the trypanosome sub-species Trypanosoma brucei gambiense and T. b. rhodesiense transmitted by tsetse flies.
G. Garrod, E. Adams, Jessica K. Lingley, I. Saldanha, S. Torr, Lucas J. Cunningham   +5 more
semanticscholar   +1 more source

Les glossines de l'agglomération brazzavilloise. III. Rôle vecteur dans les trypanosomoses animales et humaine

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1987
Depuis l'élimination en 1985 des glossines du centre ville de la capitale congolaise, la trypanosomose animale à trypanosoma congolense y a totalement disparu. Cependant, en périphérie Sud de Brazzaville parallélement à l'épizootie à t.
F. Noireau, A. Toudic, J.P. Gouteux, N. Bissadidi, Jean-Louis Frézil, J.P. Duteurtre   +5 more
doaj   +1 more source

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei.

PLoS Pathogens, 2014
Closely related African trypanosomes cause lethal diseases but display distinct host ranges. Specifically, Trypanosoma brucei brucei causes nagana in livestock but fails to infect humans, while Trypanosoma brucei gambiense and Trypanosoma brucei ...
Sam Alsford, Rachel B Currier, José Afonso Guerra-Assunção, Taane G Clark, David Horn   +4 more
doaj   +1 more source

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

mBio, 2016
African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1).
Bart Cuypers, Laurence Lecordier, Conor J. Meehan, Frederik Van den Broeck, Hideo Imamura, Philippe Büscher, Jean-Claude Dujardin, Kris Laukens, Achim Schnaufer, Caroline Dewar, Michael Lewis, Oliver Balmer, Thomas Azurago, Sardick Kyei-Faried, Sally-Ann Ohene, Boateng Duah, Prince Homiah, Ebenezer Kofi Mensah, Francis Anleah, Jose Ramon Franco, Etienne Pays, Stijn Deborggraeve   +21 more
doaj   +1 more source

A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b.
Nick Van Reet, Hélène Van de Vyver, Patient Pati Pyana, Anne Marie Van der Linden, Philippe Büscher   +4 more
doaj   +1 more source

The challenge of Trypanosoma brucei gambiense sleeping sickness diagnosis outside Africa [PDF]

The Lancet Infectious Diseases, 2003
Sleeping sickness is a lethal African disease caused by parasites of the Trypanosoma brucei subspecies, which is transmitted by tsetse flies. Occasionally, patients are reported outside Africa. Diagnosis of such imported cases can be problematic when the infection is due to Trypanosoma brucei gambiense, the chronic form of sleeping sickness found in ...
Lejon, V., Boelaert, M., Jannin, J., Moore, A., Büscher, P.   +4 more
openaire   +4 more sources