Results 71 to 80 of about 18,366 (207)

Improvement of colony management in insect mass‐rearing for sterile insect technique applications

Insect Science, Volume 32, Issue 5, Page 1476-1494, October 2025.
Abstract Sterile Insect Technique (SIT) applications against major insect pests and disease vectors rely on the cost‐effective production of high‐quality sterile males. This largely depends on the optimal management of target pest colonies by maximizing the benefits provided by a genetically rich and pathogen‐free mother colony, the presence of ...
Adly M.M. Abd‐Alla, Anne Geiger, David Haymer, Salvador Herrero, Johannes, A. Jehle, Fathiya Khamis, Pablo Liedo, Anna R. Malacrida, Flobert Njiokou, Thiago Mastrangelo, Soumaïla Pagabeleguem, Edwin M. Ramırez‐Santos, Vera I.D. Ros, Diego F. Segura, George Tsiamis, Brian L. Weiss   +16 more
wiley   +1 more source

Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016

Emerging Infectious Diseases, 2017
Human African trypanosomiasis has not been reported in Nigeria since 2012. Nevertheless, limitations of current surveillance programs mean that undetected infections may persist.
Akish Luintel, Patricia Lowe, Anneli Cooper, Annette MacLeod, Philippe Büscher, Tim Brooks, Mike Brown   +6 more
doaj   +1 more source

New tsetse (Glossina fuscipes fuscipes) genomes generated from wild and laboratory‐reared specimens

Insect Science, Volume 32, Issue 5, Page 1588-1596, October 2025.
Abstract Tsetse (Glossina spp.) are vectors of African trypanosomes that cause devastating human and animal African trypanosomiases. While much of the research to better understand tsetse genetics and physiology relies on colony‐reared flies, these flies may not represent the genetic diversity found in natural wild populations due to their long‐term ...
Daniel J. Bruzzese, Brian L. Weiss, Richard Echodu, Paul O. Mireji, Adly M.M Abd‐Alla, Serap Aksoy   +5 more
wiley   +1 more source

Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins

PLoS Neglected Tropical Diseases, 2011
The current antibody detection tests for the diagnosis of gambiense human African trypanosomiasis (HAT) are based on native variant surface glycoproteins (VSGs) of Trypanosoma brucei (T.b.) gambiense. These native VSGs are difficult to produce, and contain non-specific epitopes that may cause cross-reactions. We aimed to identify mimotopic peptides for
Van Nieuwenhove, Liesbeth, Roge, Stijn, Balharbi, Fatima, Dieltjens, Tessa, Laurent, Thierry, Guisez, Yves, Buscher, Philippe, Lejon, Veerle   +7 more
openaire   +5 more sources

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

Drug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp, Helena D. Janse van Rensburg, Simon S. Mnyakeni‐Moleele, Keisuke Suganuma, David D. N'Da   +4 more
wiley   +1 more source

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

PLoS Neglected Tropical Diseases, 2011
BackgroundThe three sub-species of Trypanosoma brucei are important pathogens of sub-Saharan Africa. T. b. brucei is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. T. b. rhodesiense and T.
Paul Capewell, Nicola J Veitch, C Michael R Turner, Jayne Raper, Matthew Berriman, Stephen L Hajduk, Annette MacLeod   +6 more
doaj   +1 more source

Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo

Parasites & Vectors, 2012
Background The Malanga sleeping sickness focus of the Democratic Republic of Congo has shown an epidemic evolution of disease during the last century. However, following case detection and treatment, the prevalence of the disease decreased considerably ...
Simo Gustave, Silatsa Barberine, Flobert Njiokou, Lutumba Pascal, Mansinsa Philemon, Madinga Joule, Manzambi Emile, De Deken Reginald, Asonganyi Tazoacha   +8 more
doaj   +1 more source

Human African trypanosomiasis in two historical foci of the estuaire province, gabon: A case report

SAGE Open Medical Case Reports, 2020
Human African Trypanosomiasis (HAT) is an infectious disease due to a protozoa parasite of the Trypanosoma genus. In West and Central Africa, this disease is caused by the subspecies Trypanosoma brucei gambiense .
Berthe Amélie Iroungou, Larson Boundenga, Laurette Guignali Mangouka, Berthold Bivigou-Mboumba, Jean Raymond Nzenze, Gael Darren Maganga   +5 more
doaj   +1 more source

Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad

Parasites & Vectors, 2023
Background Human African trypanosomiasis (HAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies in sub-Saharan West Africa. In southern Chad the most active and persistent focus is the Mandoul focus, with
Mahamat Hissene Mahamat, Adeline Ségard, Jean-Baptiste Rayaisse, Rafael Argiles-Herrero, Andrew Gordon Parker, Philippe Solano, Adly Mohamed Mohamed Abd-Alla, Jérémy Bouyer, Sophie Ravel   +8 more
doaj   +1 more source

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study

PLoS Neglected Tropical Diseases, 2016
Background A major challenge in the control of human African trypanosomiasis (HAT) is lack of reliable diagnostic tests that are rapid and easy to use in remote areas where the disease occurs.
S. Bisser, C. Lumbala, Etienne Nguertoum, V. Kande, Laurence Flévaud, G. Vatunga, M. Boelaert, P. Büscher, T. Josenando, P. Bessell, S. Biéler, J. Ndung'u   +11 more
semanticscholar   +1 more source