Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia [PDF]
Emerging Infectious Diseases, 2023 We report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available.
Adugna Abera +26 more
doaj +4 more sources
Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda [PDF]
Tropical Medicine and Infectious Disease, 2020 We carried out a baseline survey of cattle in Kaberamaido district, in the context of controlling the domestic animal reservoir of Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) towards elimination.
Enock Matovu +5 more
doaj +4 more sources
Using molecular data for epidemiological inference: assessing the prevalence of Trypanosoma brucei rhodesiense in tsetse in Serengeti, Tanzania. [PDF]
PLoS Neglected Tropical Diseases, 2012 BackgroundMeasuring the prevalence of transmissible Trypanosoma brucei rhodesiense in tsetse populations is essential for understanding transmission dynamics, assessing human disease risk and monitoring spatio-temporal trends and the impact of control ...
Harriet K Auty +5 more
doaj +8 more sources
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by Trypanolytic factor 1 [PDF]
, 2011 <p><b>Background:</b> The three sub-species of <i>Trypanosoma brucei</i> are important pathogens of sub-Saharan Africa. <i>T. b.
A Cooper +77 more
core +63 more sources
Dynamical and optimal control analysis of a seasonal Trypanosoma brucei rhodesiense model
Mathematical Biosciences and Engineering, 2020 The effects of seasonal variations on the epidemiology of Trypanosoma brucei rhodesiense disease is well documented. In particular, seasonal variations alter vector development rates and behaviour, thereby influencing the transmission dynamics of the ...
Mlyashimbi Helikumi +3 more
doaj +3 more sources
Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci. [PDF]
PLoS Neglected Tropical Diseases, 2013 African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
Craig W Duffy +8 more
doaj +9 more sources
Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense [PDF]
PLoS Neglected Tropical Diseases, 2008 Loop-mediated isothermal amplification (LAMP) of DNA is a novel technique that rapidly amplifies target DNA under isothermal conditions. In the present study, a LAMP test was designed from the serum resistance-associated (SRA) gene of Trypanosoma brucei ...
Armstrong, T. +5 more
core +5 more sources
De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. [PDF]
PLoS ONE, 2016 BACKGROUND:Trypanosoma brucei is a eukaryotic pathogen which causes African trypanosomiasis. It is notable for its variant surface glycoprotein (VSG) coat, which undergoes antigenic variation enabled by a large suite of VSG pseudogenes, allowing for ...
Mark Sistrom +5 more
doaj +7 more sources
Persistently High Incidences of Trypanosoma brucei rhodesiense Sleeping Sickness With Contrasting Focus-Dependent Clinical Phenotypes in Malawi [PDF]
Frontiers in Tropical Diseases, 2022 Background Human African trypanosomiasis (HAT) has caused social–economic burden in remote rural communities mostly in sub-Saharan Africa for over a century.
Peter Nambala +8 more
openalex +2 more sources
Whole-Genome Sequencing of
mBio, 2013 Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Ian Goodhead +10 more
doaj +5 more sources