Results 21 to 30 of about 14,712 (223)

Molecular docking to homology models of human and Trypanosoma brucei ERK8 that identified ortholog-specific inhibitors. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a lethal disease caused by two vector-borne parasites: Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense. The limited number of antitrypanosomal therapies for treating
Matthew Merski, Zachary B Mackey
doaj   +2 more sources

Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods. [PDF]

open access: goldPLoS Negl Trop Dis, 2018
Mulindwa J   +10 more
europepmc   +3 more sources

Therapeutic Strategies against Leishmania and Trypanosoma

open access: yesPathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos   +5 more
doaj   +1 more source

Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa

open access: yesFrontiers in Veterinary Science, 2021
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi   +23 more
doaj   +1 more source

Decolonising Parasitology: The Case of Trypanosoma brucei rhodesiense

open access: yesTrends in Parasitology, 2021
Trypanosoma brucei rhodesiense was named after Rhodesia which, in turn, was named after the British imperialist and white supremacist Cecil Rhodes. In the light of the Black Lives Matter movement and contemporary consciousness of postcolonial legacy, it seems opportune to reconsider the subspecies name. Pros and cons of renaming T. b.
Steverding, Dietmar, Tyler, Kevin M.
openaire   +4 more sources

Localization of serum resistance-associated protein in Trypanosoma brucei rhodesiense and transgenic Trypanosoma brucei brucei. [PDF]

open access: yesCell Microbiol, 2015
African trypanosomes infect a broad range of mammals, but humans and some higher primates are protected by serum trypanosome lytic factors that contain apolipoprotein L1 (ApoL1). In the human-infective subspecies of Trypanosoma brucei, Trypanosoma brucei rhodesiense, a gene product derived from the variant surface glycoprotein gene family member, serum
Bart JM   +8 more
europepmc   +6 more sources

Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases [PDF]

open access: yes, 2020
Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported
Gao, J-M   +5 more
core   +2 more sources

Recommendations for control of East African sleeping sickness in Uganda

open access: yesJournal of Global Infectious Diseases, 2010
East African sleeping sickness, caused by Trypanosoma brucei rhodesiense, is prominent in Uganda and poses a serious public health challenge in the region.
Simon Kotlyar
doaj   +3 more sources

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