Results 31 to 40 of about 14,712 (223)

Suramin action in African trypanosomes involves a RuvB-like DNA helicase

International Journal for Parasitology: Drugs and Drug Resistance, 2023
Suramin is one of the oldest drugs in use today. It is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei rhodesiense, and it is also used for surra in camels caused by Trypanosoma evansi ...
Anna Albisetti, Silvan Hälg, Martin Zoltner, Pascal Mäser, Natalie Wiedemar   +4 more
doaj   +1 more source

Wild chimpanzees are infected by Trypanosoma brucei

International Journal for Parasitology: Parasites and Wildlife, 2015
Although wild chimpanzees and other African great apes live in regions endemic for African sleeping sickness, very little is known about their trypanosome infections, mainly due to major difficulties in obtaining their blood samples.
Milan Jirků, Jan Votýpka, Klára J. Petrželková, Kateřina Jirků-Pomajbíková, Eva Kriegová, Roman Vodička, Felix Lankester, Siv Aina J. Leendertz, Roman M. Wittig, Christophe Boesch, David Modrý, Francisco J. Ayala, Fabian H. Leendertz, Julius Lukeš   +13 more
doaj   +1 more source

Molecular epidemiology of African sleeping sickness [PDF]

, 2009
Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT, G. HIDE, Gibson, Hide, Mehlitz, Morrison   +5 more
core   +2 more sources

Multiple evolutionary origins of Trypanosoma evansi in Kenya.

PLoS Neglected Tropical Diseases, 2017
Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world.
Christine M Kamidi, Norah P Saarman, Kirstin Dion, Paul O Mireji, Collins Ouma, Grace Murilla, Serap Aksoy, Achim Schnaufer, Adalgisa Caccone   +8 more
doaj   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +4 more sources

Genetic diversity among Trypanosoma brucei rhodesiense isolates from Tanzania [PDF]

Parasitology, 1997
We compared 19 stocks of Trypanosoma brucei rhodesiense collected in 1991 and 1994 from Tanzania with representative stocks from other foci of Rhodesian sleeping sickness in Zambia, Kenya and Uganda. Stocks were characterized by isoenzyme electrophoresis, restriction fragment length polymorphisms in variant surface glycoprotein genes and ...
E K, Komba, S N, Kibona, A K, Ambwene, J R, Stevens, W C, Gibson   +4 more
openaire   +5 more sources

The burden of human African trypanosomiasis.

PLoS Neglected Tropical Diseases, 2008
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre, Beatrix V Wissmann, Susan C Welburn, Pascal Lutumba   +3 more
doaj   +1 more source

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
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core   +1 more source

Comparative analysis of cerebrospinal fluid from the meningo-encephalitic stage of T. b. gambiense and rhodesiense sleeping sickness patients using TMT quantitative proteomics

Data in Brief, 2015
The quantitative proteomics data here reported are part of a research article entitled “Increased acute immune response during the meningo-encephalitic stage of Trypanosoma brucei rhodesiense sleeping sickness compared to Trypanosoma brucei gambiense ...
Natalia Tiberti, Jean-Charles Sanchez
doaj   +1 more source

A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b.
Nick Van Reet, Hélène Van de Vyver, Patient Pati Pyana, Anne Marie Van der Linden, Philippe Büscher   +4 more
doaj   +1 more source