Drug combination studies of PS-1 and quercetin against rhodesain of Trypanosoma brucei rhodesiense
Natural Product Research, 2021 Rhodesain is a cysteine protease crucial for the survival of Trypanosoma brucei rhodesiense, the parasite able to induce the acute lethal form of Human African Trypanosomiasis.
Carla Di Chio +5 more
semanticscholar +1 more source
A mathematical model for evaluating the role of trypanocide treatment of cattle in the epidemiology and control of Trypanosoma brucei rhodesiense and T. b. gambiense sleeping sickness in Uganda [PDF]
Parasite Epidemiol Control, 2019 Julianne Meisner +2 more
semanticscholar +2 more sources
Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei [PDF]
, 2021 Trans-splicing of leader sequences onto the 59ends of mRNAs is a widespread phenomenon in protozoa, nematodes and some chordates. Using parallel sequencing we have developed a method to simultaneously map 59splice sites and analyze the corresponding gene expression profile, that we term spliced leader trapping (SLT).
arxiv +1 more source
Recommendations for control of East African sleeping sickness in Uganda
Journal of Global Infectious Diseases, 2010 East African sleeping sickness, caused by Trypanosoma brucei rhodesiense, is prominent in Uganda and poses a serious public health challenge in the region.
Simon Kotlyar
doaj +3 more sources
Wild chimpanzees are infected by Trypanosoma brucei
International Journal for Parasitology: Parasites and Wildlife, 2015 Although wild chimpanzees and other African great apes live in regions endemic for African sleeping sickness, very little is known about their trypanosome infections, mainly due to major difficulties in obtaining their blood samples.
Milan Jirků +13 more
doaj +1 more source
Molecular epidemiology of African sleeping sickness [PDF]
, 2009 Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT +5 more
core +2 more sources
Multiple evolutionary origins of Trypanosoma evansi in Kenya.
PLoS Neglected Tropical Diseases, 2017 Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world.
Christine M Kamidi +8 more
doaj +1 more source
Advances in Differential Equations, 2020 Temperature is one of the integral environmental drivers that strongly affect the distribution and density of tsetse fly population. Precisely, ectotherm performance measures, such as development rate, survival probability and reproductive rate, increase
Mlyashimbi Helikumi +3 more
semanticscholar +1 more source
The burden of human African trypanosomiasis.
PLoS Neglected Tropical Diseases, 2008 Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre +3 more
doaj +1 more source
Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases [PDF]
, 2020 Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported
Gao, J-M +5 more
core +2 more sources