Results 1 to 10 of about 26,119 (196)

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone. [PDF]

open access: yesDrug Dev Res
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Aucamp J   +4 more
europepmc   +2 more sources

A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction [PDF]

open access: yesMicrobiology Spectrum
Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both ...
Nathan P. Crilly   +7 more
doaj   +2 more sources

Africa and the Cattle Without History [PDF]

open access: yesGlobal Environment
African historiography of tsetse-borne trypanosomiasis has yet to fully embrace the genetic basis of cattle tolerance to the disease due to the literature’s emphasis on human illness and landscape modification.
Tad Brown
doaj   +2 more sources

Evaluating paratransgenesis as a potential control strategy for African trypanosomiasis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2013
Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this ...
Jan Medlock   +4 more
doaj   +1 more source

Unusual neurological presentation of second stage African trypanosomiasis in a young boy: a case report

open access: yesBMC Pediatrics, 2022
Background In South Sudan, sleeping sickness is a frequent condition caused by human African trypanosomiasis. There are two stages that are well-known.
Etedal Ahmed A. Ibrahim   +4 more
doaj   +1 more source

Insights into the Control and Management of Human and Bovine African Trypanosomiasis in Zambia between 2009 and 2019—A Review

open access: yesTropical Medicine and Infectious Disease, 2020
Tsetse transmitted trypanosomiasis is a fatal disease commonly known as Nagana in cattle and sleeping sickness in humans. The disease threatens food security and has severe economic impact in Africa including most parts of Zambia.
Gloria M. Mulenga   +5 more
doaj   +1 more source

Potential applicability of the importation risk index for predicting the risk of rarely imported infectious diseases

open access: yesBMC Public Health, 2023
Background There have been many prediction studies for imported infectious diseases, employing air-travel volume or the importation risk (IR) index, which is the product of travel-volume and disease burden in the source countries, as major predictors ...
Kyung-Duk Min   +4 more
doaj   +1 more source

Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts

open access: yesVirulence, 2023
African trypanosomes are vector-borne protozoa, which cause significant human and animal disease across sub-Saharan Africa, and animal disease across Asia and South America.
Liam J. Morrison   +3 more
doaj   +1 more source

Transmission concomitante de trypanosomose humaine et animale : le foyer de Mandoul au Tchad

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2014
La trypanosomose est une maladie qui affecte à la fois l’homme et les animaux. Elle est provoquée par Trypanosoma sp. et cycliquement transmise par un vecteur, la glossine.
Peka Mallaye   +4 more
doaj   +1 more source

Current Treatments to Control African Trypanosomiasis and One Health Perspective

open access: yesMicroorganisms, 2022
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei.
Alberto Venturelli   +9 more
doaj   +1 more source

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