Results 81 to 90 of about 26,119 (196)
Journal of the American Medical Association, 1915 Patient. —I. S., No. 181943, man, negro, aged 35, native of Cape Verde Islands, was admitted to the Massachusetts State Infirmary from New Bedford, Oct. 7, 1914. The patient was unable to understand English, and as a good Portuguese interpreter was not available at the time, his history could not be obtained.
openaire +3 more sources
Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]
, 2014 It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer +32 more
core +1 more source
Health Science Reports, Volume 8, Issue 5, May 2025.ABSTRACT Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains ...
Sabrina Sharmin +3 more
wiley +1 more source
Pharmacological Approaches to Antitrypanosomal Chemotherapy
Memorias do Instituto Oswaldo Cruz, 1999 There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the identification and characterization of novel drug targets for rational chemotherapy and ...
Simon L Croft
doaj +1 more source
Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.Ticks were collected between October 2020 and November 2022, from cattle, goats and sheep in the Sahelian, Sudano‐Sahelian and Sudanian zones, and tested for CCHFV infection. A total of 3632 animals were examined and 35.3% (95% CI: 33.8–36.9) found tick‐infested.
Aliou Khoule +9 more
wiley +1 more source
Host genetics in African trypanosomiasis
Infection, Genetics and Evolution, 2008 In Africa, the protozoan parasite of the genus Trypanosoma causes animal (AAT) and human African trypanosomiasis (HAT). These diseases are responsible for considerable mortality and economic losses, and until now the drugs commonly used have often been very toxic and expensive, with no vaccine available.
Courtin, D. +5 more
openaire +5 more sources
Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
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Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem, Volume 26, Issue 7, April 1, 2025.Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen +8 more
wiley +1 more source
Through the dark continent: African trypanosome development in the tsetse fly [PDF]
, 2013 African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
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Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
International Journal of Infectious Diseases, 2019 We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014.
Nian Chen +4 more
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