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Systemic tryptophan homeostasis
Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin.
Simon Klaessens+9 more
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Background Tryptophan catabolites suppress immunity. Therefore, blocking tryptophan catabolism with indoleamine 2,3-dioxygenase (IDO) inhibitors is pursued as an anticancer strategy.Methods The intracellular level of tryptophan and kynurenine was ...
Yan Huang+10 more
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Immunomodulatory, behavioral, and nutritional response of tryptophan application on poultry [PDF]
Tryptophan is an essential amino acid for all animals that was discovered through casein hydrolysis. The use of tryptophan as feed additives has been attracting the attention of many nutritionists because it cannot be synthesized enough in an animal's ...
Nguyen Thuy Linh+2 more
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Effect of Varying Levels of Dietary Tryptophan on Aggression and Abnormal Behavior in Growing Pigs
Body lesions, resulting from tail-biting and ear-biting, can result in decreased health and welfare in pigs. Tryptophan, an indispensable amino acid, is needed to support protein deposition, and the synthesis of the neurotransmitter serotonin, which is ...
Maggie Henry+4 more
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Determination of tryptophan in milk
Tryptophan or L-tryptophan is one of the essential amino acids for the human body. An important component of the human diet, L-tryptophan is not only involved in protein synthesis in the body, but is also crucial for a number of metabolic functions.
N. P. Kvitkovskaya+3 more
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Tryptophan indirectly increases plasma calcium levels, which may improve sow health, and melatonin production, which may improve piglet survival when supplemented during late gestation and lactation.
Amy L. Munn+2 more
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Modulation of tryptophan/serotonin pathway by probiotic supplementation in human immunodeficiency virus-positive patients: preliminary results of a new study approach [PDF]
Background: To date, no data are available regarding the effects of probiotics on the pathway of tryptophan/serotonin metabolism among human immunodeficiency virus (HIV) 1–infected individuals.
Cavallari, Eugenio Nelson+14 more
core +9 more sources
Alterations in brain/gut/microbiota axis are linked to Irritable Bowel Syndrome (IBS) physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio-depressive comorbidities may persist despite pathogen clearance leading to Post ...
Maëva Meynier+21 more
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Indoleamine 2, 3-dioxygenase 1 inhibitory compounds from natural sources
L-tryptophan metabolism is involved in the regulation of many important physiological processes, such as, immune response, inflammation, and neuronal function.
Ying Tan+4 more
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Biochemical and physicochemical indicators of the quality of milk and meat obtained from cows with brucellosis [PDF]
Background and Aim: Brucellosis is a disease occurring worldwide. Although it is mainly a cattle disease, it is extremely dangerous for humans. Milk and meat can be contaminated with Brucella.
Valeriy Alexandrovich Agoltsov+4 more
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