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Optimal Tryptophan Improved Growth and Regulated Agonistic Behavior of Oriental River Prawn, Macrobrachium nipponense [PDF]

open access: yesAquaculture Nutrition
Tryptophan, recognized as the third limiting amino acid, plays a crucial physiological function. The optimal tryptophan requirement for oriental river prawn (Macrobrachium nipponense) was assessed, and its impact on agonistic behavior was evaluated in ...
Shiqian Cao   +5 more
doaj   +2 more sources

Systemic tryptophan homeostasis

open access: yesFrontiers in Molecular Biosciences, 2022
Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin.
Simon Klaessens   +9 more
doaj   +4 more sources

Metabolic and Stress Responses in Senegalese Soles (Solea senegalensis Kaup) Fed Tryptophan Supplements: Effects of Concentration and Feeding Period [PDF]

open access: yesAnimals, 2019
The objective of this study was to assess the impact of different dietary Trp concentrations on the stress and metabolism response of juvenile Senegalese soles (Solea senegalensis).
Marcelino Herrera   +6 more
doaj   +6 more sources

Immunomodulatory, behavioral, and nutritional response of tryptophan application on poultry [PDF]

open access: yesVeterinary World, 2021
Tryptophan is an essential amino acid for all animals that was discovered through casein hydrolysis. The use of tryptophan as feed additives has been attracting the attention of many nutritionists because it cannot be synthesized enough in an animal's ...
Nguyen Thuy Linh   +2 more
doaj   +1 more source

Effect of Varying Levels of Dietary Tryptophan on Aggression and Abnormal Behavior in Growing Pigs

open access: yesFrontiers in Veterinary Science, 2022
Body lesions, resulting from tail-biting and ear-biting, can result in decreased health and welfare in pigs. Tryptophan, an indispensable amino acid, is needed to support protein deposition, and the synthesis of the neurotransmitter serotonin, which is ...
Maggie Henry   +4 more
doaj   +1 more source

Tryptophan potentiates CD8+ T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Tryptophan catabolites suppress immunity. Therefore, blocking tryptophan catabolism with indoleamine 2,3-dioxygenase (IDO) inhibitors is pursued as an anticancer strategy.Methods The intracellular level of tryptophan and kynurenine was ...
Yan Huang   +10 more
doaj   +1 more source

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

open access: yesNature, 2022
AbstractActivated T cells secrete interferon-γ, which triggers intracellular tryptophan shortage by upregulating the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme1–4. Here we show that despite tryptophan depletion, in-frame protein synthesis continues across tryptophan codons.
Abhijeet Pataskar   +23 more
openaire   +8 more sources

Modulation of tryptophan/serotonin pathway by probiotic supplementation in human immunodeficiency virus-positive patients: preliminary results of a new study approach [PDF]

open access: yes, 2017
Background: To date, no data are available regarding the effects of probiotics on the pathway of tryptophan/serotonin metabolism among human immunodeficiency virus (HIV) 1–infected individuals.
Cavallari, Eugenio Nelson   +14 more
core   +9 more sources

Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism

open access: yesFrontiers in Immunology, 2022
Ulcerative colitis (UC) is a chronic and recurrent inflammatory disorder in the gastrointestinal tract. Here, we examined the pharmacological effects of ginsenoside Rg1, a natural compound with low bioavailability, on the acute experimental colitis mice ...
Hao Cheng   +9 more
doaj   +1 more source

Growth performance and small intestinal morphology of native chickens after feed supplementation with tryptophan and threonine during the starter phase [PDF]

open access: yesVeterinary World, 2020
Background and Aim: The amino acid content of feed can affect growth performance of poultry during the first 6 weeks of life or the starter phase.
Charles V. Lisnahan, Oktovianus R. Nahak
doaj   +1 more source

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