Results 11 to 20 of about 222,637 (336)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls   +9 more
wiley   +1 more source

Indoleamine 2, 3-dioxygenase 1 inhibitory compounds from natural sources

open access: yesFrontiers in Pharmacology, 2022
L-tryptophan metabolism is involved in the regulation of many important physiological processes, such as, immune response, inflammation, and neuronal function.
Ying Tan   +4 more
doaj   +1 more source

Biochemical and physicochemical indicators of the quality of milk and meat obtained from cows with brucellosis [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Brucellosis is a disease occurring worldwide. Although it is mainly a cattle disease, it is extremely dangerous for humans. Milk and meat can be contaminated with Brucella.
Valeriy Alexandrovich Agoltsov   +4 more
doaj   +1 more source

Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism

open access: yesFrontiers in Immunology, 2022
Ulcerative colitis (UC) is a chronic and recurrent inflammatory disorder in the gastrointestinal tract. Here, we examined the pharmacological effects of ginsenoside Rg1, a natural compound with low bioavailability, on the acute experimental colitis mice ...
Hao Cheng   +9 more
doaj   +1 more source

Glycated Tryptophan in the Plasma of Chickens Fed Tryptophan-excess Diets

open access: yesThe Journal of Poultry Science, 2015
When tryptophan is glycated with glucose, it results in forming two types of glycated tryptophan, glucose-tryptophan Amadori product and (1R, 3S)-1-(D- gluco-1,2,3,4,5-pentahydroxypentyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (PHP-THβC ...
Ryosuke Makino   +7 more
doaj   +1 more source

Ultraviolet superradiance from mega-networks of tryptophan in biological architectures [PDF]

open access: yes, 2023
Networks of tryptophan -- an aromatic amino acid with strong fluorescent response -- are ubiquitous in biological systems, forming diverse architectures in transmembrane proteins, cytoskeletal filaments, sub-neuronal elements, photoreceptor complexes, virion capsids, and other cellular structures.
arxiv   +1 more source

The relationship between Type D personality with atherosclerotic plaque and cardiovascular events: The mediation effect of inflammation and kynurenine/tryptophan metabolism

open access: yesFrontiers in Cardiovascular Medicine, 2022
PurposeCardiovascular events and coronary plaque vulnerability are linked to Type D personality. However, the fundamental mechanism has not been clarified.
Yini Wang   +10 more
doaj   +1 more source

Tryptophan to Tryptophan Hole Hopping in an Azurin Construct

open access: yesThe Journal of Physical Chemistry B, 2023
Electron transfer (ET) between neutral and cationic tryptophan residues in the azurin construct [ReI(H126)(CO)3(dmp)](W124)(W122)CuI (dmp = 4,7-Me2-1,10-phenanthroline) was investigated by Born-Oppenheimer quantum-mechanics/molecular mechanics/molecular dynamics (QM/MM/MD) simulations.
Martin Melčák   +5 more
openaire   +4 more sources

Detection of Two Types of Glycated Tryptophan Compounds in the Plasma of Chickens Fed Tryptophan Excess Diets

open access: yesThe Journal of Poultry Science, 2013
When tryptophan is glycated with glucose, it results in forming two types of glycated tryptophan compounds, glucose-tryptophan Amadori product and (1R, 3S)-1-(D-gluco-1,2,3,4,5-pentahydroxypentyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (PHP ...
Kazumi Kita   +6 more
doaj   +1 more source

States of quinolinic acid excess in urine: A systematic review of human studies

open access: yesFrontiers in Nutrition, 2022
IntroductionQuinolinic acid is an intermediate compound derived from the metabolism of dietary tryptophan. Its accumulation has been reported in patients suffering a broad spectrum of diseases and conditions. In this manuscript, we present the results of
Marie Christelle Saade   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy