Results 21 to 30 of about 436,973 (328)

Toward an Alternative Intrinsic Probe for Spectroscopic Characterization of a Protein [PDF]

, 2010
The intrinsic fluorescent amino acid tryptophan is the unanimous choice for the spectroscopic investigation of proteins. However, several complicacies in the interpretation of tryptophan fluorescence in a protein are inevitable and an alternative ...
Goswami, Nirmal, Makhal, Abhinandan, Pal, Samir Kumar   +2 more
core   +1 more source

One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan in Escherichia coli

Microbial Cell Factories, 2012
Background L-tryptophan is an aromatic amino acid widely used in the food, chemical and pharmaceutical industries. In Escherichia coli, L-tryptophan is synthesized from phosphoenolpyruvate and erythrose 4-phosphate by enzymes in the shikimate pathway and
Gu Pengfei, Yang Fan, Kang Junhua, Wang Qian, Qi Qingsheng   +4 more
doaj   +1 more source

The Role of Tryptophan Metabolism in Alzheimer’s Disease

Brain Sciences, 2023
The need to identify new potentially druggable biochemical mechanisms for Alzheimer’s disease (AD) is an ongoing priority. The therapeutic limitations of amyloid-based approaches are further motivating this search.
Karl Savonije, Donald F. Weaver
doaj   +1 more source

Mutational analysis of the carbohydrate binding activity of the tobacco lectin [PDF]

, 2010
At present the three-dimensional structure of the tobacco lectin, further referred to as Nictaba, and its carbohydrate-binding site are unresolved. In this paper, we propose a three-dimensional model for the Nictaba domain based on the homology between ...
Barre, Annick, Lasanajak, Yi, Proost, Paul, Rouge, Pierre, Schouppe, Dieter, Smith, David F, Van Damme, Els   +6 more
core   +2 more sources

Effects of dietary tryptophan supplementation on rectal temperature, humoral immunity, and cecal microflora composition of heat-stressed broilers

Frontiers in Veterinary Science, 2023
This trial aimed to determine the effects of tryptophan (Trp) on the rectal temperature, hormone, humoral immunity, and cecal microflora composition in broiler chickens under heat stress (HS).
Qiufen Li, Qiufen Li, Qiufen Li, Jingxin Ouyang, Jingxin Ouyang, Chenxi Deng, Chenxi Deng, Hua Zhou, Hua Zhou, Jinming You, Jinming You, Guanhong Li, Guanhong Li   +12 more
doaj   +1 more source

Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]

, 2018
BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach, Beeken, Bettenworth, Clayton, Coburn, Dąbrowski, Gupta, Hashimoto, Hou, Kim, Kim, Li, Liu, Liu, Middleton, Morgan, Nikolaus, Ren, Richard, Ruth, Schrocksnadel, Tsune, Walser, Wang, Widner, Xin   +25 more
core   +4 more sources

Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle.

PLoS Biology, 2007
Mammalian cells rely on cellular uptake of the essential amino acid tryptophan. Tryptophan sequestration by up-regulation of the key enzyme for tryptophan degradation, indoleamine 2,3-dioxygenase (IDO), e.g., in cancer and inflammation, is thought to ...
Thijs Kaper, Loren L Looger, Hitomi Takanaga, Michael Platten, Lawrence Steinman, Wolf B Frommer   +5 more
doaj   +1 more source

Electrochemical detection of kynurenic acid in the presence of tryptophan with the carbon paste electrode modified with the flower-like nanostructures of zinc oxide doped with terbium

Frontiers in Chemistry, 2023
With the help of a hydrothermal approach in this study, we could provide flower-like nanostructures (NSs) of zinc oxide (ZnO) doped with Tb (FL-NS Tb3+/ZnO).
Ali Amir Poursaeed, Shohreh Jahani, Mehran Moradalizadeh, Mehdi Shahidi Zandi, Mohammad Mehdi Foroughi   +4 more
doaj   +1 more source

The advent of phyllobilins as bioactive phytochemicals – natural compounds derived from chlorophyll in medicinal plants and food with immunomodulatory activities

Pteridines, 2023
The degradation of the green plant pigment chlorophyll has fascinated chemists and biologists alike over the last few decades. Bioactivities of the compounds formed in this biochemical degradation pathway, however, have only come to light recently. These
Vollmar Angelika M., Moser Simone
doaj   +1 more source

A synopsis of recent work on the amino acid nutrition of layers1

Journal of Applied Poultry Research, 2021
Summary: This review, a summation of work presented at the Virtual 2020 Poultry Science Association Annual Meeting, addresses changes in laying hen performance and techniques to manage hens that require fine-tuning amino acid minimums.
M.T. Kidd, R.E. Loar, II
doaj   +1 more source