Results 21 to 30 of about 24,896 (176)

The Acute Toxicity of Tetrodotoxin and Tetrodotoxin–Saxitoxin Mixtures to Mice by Various Routes of Administration

Toxins, 2018
Tetrodotoxin (TTX) is a potent neurotoxin associated with human poisonings through the consumption of pufferfish. More recently, TTX has been identified in bivalve molluscs from diverse geographical environments, including Europe, and is therefore ...
Sarah C. Finch, Michael J. Boundy, D. Tim Harwood   +2 more
doaj   +1 more source

Contribution of tetrodotoxin-resistant persistent Na+ currents to the excitability of C-type dural afferent neurons in rats

The Journal of Headache and Pain, 2022
Background Growing evidence supports the important role of persistent sodium currents (INaP) in the neuronal excitability of various central neurons.
Michiko Nakamura, Il-Sung Jang
doaj   +1 more source

Differing alterations of sodium currents in small dorsal root ganglion neurons after ganglion compression and peripheral nerve injury

Molecular Pain, 2008
Voltage-gated sodium channels play important roles in modulating dorsal root ganglion (DRG) neuron hyperexcitability and hyperalgesia after peripheral nerve injury or inflammation.
Song Xue-Jun, Huang Zhi-Jiang
doaj   +1 more source

Distribution of Tetrodotoxin in Pacific Oysters (Crassostrea gigas)

Marine Drugs, 2021
A potent and heat-stable tetrodotoxin (TTX) has been found to accumulate in various marine bivalve species, including Pacific oysters (Crassostrea gigas), raising a food safety concern.
Monika Dhanji-Rapkova, Andrew D. Turner, Craig Baker-Austin, Jim F. Huggett, Jennifer M. Ritchie   +4 more
doaj   +1 more source

La serpiente y el arco iris (1988): un modelo fisiopatológico por sobredosis de tetrodotoxina

Revista de Medicina y Cine / Journal of Medicine and Movies
La Serpiente y el Arco Iris (1988) de Wes Craven supone un modelo docente atractivo que combina la farmacología y las alteraciones fisiológicas en muchos sistemas funcionales. Basada en un hecho real, este clásico del terror convertido en una película de
Carmen Fernández-Martos, Nora Suleiman-Martos, José Luis Gómez-Urquiza, Isabel Prieto-Gómez, Manuel Ramírez-Sánchez, Ana Belén Segarra-Robles, Francisco García-Cózar, Germán Domínguez-Vías   +7 more
doaj   +1 more source

Changes in tetrodotoxin-resistant C-fibre activity during fatiguing isometric contractions in the rat. [PDF]

PLoS ONE, 2013
It is by now well established that tetrodotoxin-resistant (TTX-R) afferent fibres from muscle in the rat exhibit a multisensitive profile, including nociception.
Ivana Kalezic, Heinz Steffens
doaj   +1 more source

Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata

Marine Drugs, 2013
The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor, Susanna A. Wood, Lauren Salvitti, David I. Taylor, Janet Adamson, Paul McNabb, Stephen Craig Cary   +6 more
doaj   +1 more source

Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Marine Drugs, 2018
Postherpetic neuralgia (PHN) is nerve pain caused by a reactivation of the varicella zoster virus. Medications are used to reduce PHN but their use is limited by serious side effects.
Bihong Hong, Jipeng Sun, Hongzhi Zheng, Qingqing Le, Changsen Wang, Kaikai Bai, Jianlin He, Huanghuang He, Yanming Dong   +8 more
doaj   +1 more source

Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea)

Toxins, 2021
Nemertea is a phylum of marine worms whose members bear various toxins, including tetrodotoxin (TTX) and its analogues. Despite the more than 30 years of studying TTXs in nemerteans, many questions regarding their functions and the mechanisms ensuring ...
Anna E. Vlasenko, Vasiliy G. Kuznetsov, Grigorii V. Malykin, Alexandra O. Pereverzeva, Peter V. Velansky, Konstantin V. Yakovlev, Timur Yu. Magarlamov   +6 more
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source