Interaction of human heat shock protein 70 with tumor-associated peptides [PDF]
Molecular chaperones of the heat shock protein 70 (Hsp70) family play a crucial role in the presentation of exogenous antigenic peptides by antigen-presenting cells (APCs).
Manzenrieder, Florian +20 more
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Tumor-Associated Macrophages as Major Immunosuppressive Cells in the Tumor Microenvironment
Within the tumor microenvironment, myeloid cells constitute a dynamic immune population characterized by a heterogeneous phenotype and diverse functional activities. In this review, we consider recent literature shedding light on the increasingly complex
Dipti Athavale +5 more
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Etude des mécanismes cellulaires et moléculaires de la migration des macrophages humains dans des environnements en trois dimensions [PDF]
L'infiltration tissulaire des macrophages est un facteur aggravant dans de nombreuses pathologies telles que les maladies inflammatoires chroniques ou le cancer.
Guiet, Romain
core
The inflammatory infiltrate of high-grade serous carcinoma omental metastasis [PDF]
PhDThe aim of this thesis is to investigate the role of inflammatory infiltrates and chemokines in metastasis of high-grade serous ovarian cancer, HGSC, to the omentum using human tissue biopsies and a 3- dimensional (3D) cell culture model.
Everitt, Gemma Louise Ann
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Corrigendum: Tumor-Associated Macrophages in Tumor Immunity
Yueyun Pan +5 more
doaj +1 more source
Nanomedicine engulfed by macrophages for targeted tumor therapy
Siwen Li,1,* Song Feng,1,* Li Ding,1 Yuxi Liu,1 Qiuyun Zhu,1 Zhiyu Qian,2 Yueqing Gu1 1Department of Biomedical Engineering, China Pharmaceutical University, 2Department of Biomedical Engineering, School of Automation, Nanjing University of Aeronautics ...
Liu Y +6 more
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Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang +8 more
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Tumor-associated macrophages express restricted Ig repertoires.
(A) RT-PCR expression profiling of TAM cell preparations for B cell (CD19, CD22), T cell (CD2) and monocyte/ macrophage marker genes (CD14, CD68), respectively, demonstrates absence of detectable quantities of B or T cells.
Tina Fuchs (196304) +11 more
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Tumor-associated macrophages and microglia : double-edged sword in tumor evolvement and invasion
Tumor-associated macrophages (TAMs) are among the most abundant cell types in the tumor microenvironment. TAM infiltration is usually linked to tumor progression, metastasis and poor clinical outcome in most human cancers.
Tatjana Wallmann (18677980)
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Introduction The regulatory role of miR-182 in breast cancer malignancy and macrophage reprogramming is well established. However, the mechanisms through which miR-182 overexpression in tumor cells influences macrophage polarization remain elusive ...
Lei Qiao +5 more
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