Results 31 to 40 of about 24,022 (284)

Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]

, 2011
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E., Smith, H., Ji, Minjun, Mike Doenhoff, Emily Dawson, Claire Alexander, Gilis, Henk, van Gool, T., Cara Aitken (135264), Grant Spence, Aitken, Cara, Aitken, C., Bailey, W., Cara Aitken, Minjun Ji (135275), Spence, G., Spence, Grant, Henk Gilis, Tom van Gool, Doenhoff, M., Claire Alex, Wendi Bailey, Mike Doenhoff (135259), Gilis, H., Huw Smith, Doenhoff, Mike, van Gool, Tom, Dawson, Emily, Smith, Huw, Tom van Gool (135295), Henk Gilis (135283), Claire Alexander (20985), Minjun Ji, Bailey, Wendi, Grant Spence (135288), Alexander, C., Ji, M., Huw Smith (135256), Wendi Bailey (135270), Emily Dawson (135279), Alexander, Claire   +40 more
core   +1 more source

Animal lectins as cell adhesion molecules [PDF]

, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Expression analysis of carbohydrate antigens in ductal carcinoma in situ of the breast by lectin histochemistry

BMC Cancer, 2008
Background The number of breast cancer patients diagnosed with ductal carcinoma in situ (DCIS) continues to grow. Laboratory and clinical data indicate that DCIS can progress to invasive disease.
Kieber-Emmons Thomas, Siegel Eric, Korourian Soheila, Monzavi-Karbassi Behjatolah   +3 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Tumor-associated Carbohydrate Antigens: Sialyl Le^a and T/Tn Antigens in Canine Mammary Tumors [PDF]

Veterinary Pathology, 2009
Twenty-eight canine mammary tubulopapillary carcinomas and 14 simple adenomas were studied by immunohistochemistry for the expressions of the tumor-associated carbohydrate antigens. Sialyl Lea was detected in 71.42% of the malignant and 92.84% of the benign tumors.
M, Nowak, J, Madej, P, Dziegiel, W, Lopuszynski, A, Rodo, M, Ugorski   +5 more
openaire   +2 more sources

Tumor-Associated Glycans and Immune Surveillance

Vaccines, 2013
Changes in cell surface glycosylation are a hallmark of the transition from normal to inflamed and neoplastic tissue. Tumor-associated carbohydrate antigens (TACAs) challenge our understanding of immune tolerance, while functioning as immune targets that
Anastas Pashov, Behjatolah Monzavi-Karbassi, Thomas Kieber-Emmons   +2 more
doaj   +1 more source

Niosomes as Biocompatible Scaffolds for the Multivalent Presentation of Tumor-Associated Antigens (TACAs) to the Immune System [PDF]

, 2023
Fully synthetic tumor-associated carbohydrate antigen (TACA)-based vaccines are a promising strategy to treat cancer. To overcome the intrinsic low immunogenicity of TACAs, the choice of the antigens' analogues and multivalent presentation have been ...
Lombardi G., Maestrelli F., Fallarini S., Nativi C., Papi F., Natali F., Licciardi F.   +6 more
core   +1 more source

Colorectal Cancer (CRC): Investigating the Expression of the Suppressor of Fused (SuFu) Gene and Its Relationship with Several Inflammatory Blood-Based Biomarkers

Biomedicines, 2023
Background: Suppressor of fused (SuFu) is a tumor-suppressor gene that regulates hedgehog signaling. Its involvement in some malignancies is broadly accepted. However, its association with colorectal cancer (CRC) pathogenesis is not clear.
Tahseen Bilal Rather, Ishrat Parveiz, Gulzar A Bhat, Gowhar Rashid, Kulsum Akhtar, Rizwanul Haque, Mohammad Shamsul Ola, Mehboob Ali, Rauf A Wani, Ishrat Younas Khan, Syed Besina, Syed Mudassar   +11 more
doaj   +1 more source

State of the Art in CAR-T Cell Therapy for Solid Tumors: Is There a Sweeter Future?

Cells
Chimeric antigen receptor (CAR)-T cell therapy has proven to be a powerful treatment for hematological malignancies. The situation is very different in the case of solid tumors, for which no CAR-T-based therapy has yet been approved.
Beatriz Amorós-Pérez, Benigno Rivas-Pardo, Manuel Gómez del Moral, José Luis Subiza, Eduardo Martínez-Naves   +4 more
doaj   +1 more source