Results 31 to 40 of about 9,201,633 (292)

A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express α-gal epitopes. [PDF]

PLoS ONE, 2017
Single-agent immunotherapy is ineffective against poorly immunogenic cancers, including pancreatic ductal adenocarcinoma (PDAC). The aims of this study were to demonstrate the feasibility of production of novel autologous tumor lysate vaccines from ...
Kenta Furukawa, Masahiro Tanemura, Eiji Miyoshi, Hidetoshi Eguchi, Hiroaki Nagano, Katsuyoshi Matsunami, Satoshi Nagaoka, Daisaku Yamada, Tadafumi Asaoka, Takehiro Noda, Hiroshi Wada, Koichi Kawamoto, Kunihito Goto, Kiyomi Taniyama, Masaki Mori, Yuichiro Doki   +15 more
doaj   +1 more source

Lectin ligands: New insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins [PDF]

, 1998
The mysteries of the functions of complex glycoconjugates have enthralled scientists over decades. Theoretical considerations have ascribed an enormous capacity to store information to oligosaccharides, In the interplay with lectins sugar-code words of ...
Kozár, T., Frank, M., Gabius, H.-J., Kaltner, Herbert, Bovin, Nicolai V., Lieth, C.-W. von der, Burchert, M., Tajkhorshid, Emadeddin, Gilleron, M., Siebert, H.-C., Tajkhorshid, E., Kayser, Gian, Siebert, H. C., Vliegenthart, JFG, Vliegenthart, J.F.G., Bovin, N.V., Vliegenthart, Johannes F. G., Gabius, Hans-Joachim, Bovin, N. V., Burchert, Maria, Kaltner, H., Gilleron, Martine, von Der Lieth, C.-W., Kayser, G., Tajkhorshid, Emad, Lieth, Claus-Wilhelm von der, Leith, C.-W. von der, N.V. Bovin, J.F.G. Vliegenthart, C.-W. von der Lieth, T. Kožár, M. Frank, E. Tajkhorshid, H.-C. Siebert, M. Gilleron, H. Kaltner, M. Burchert, H.-J. Gabius, G. Kayser   +38 more
core   +2 more sources

Carbohydrate antigen 15-3 as a marker of disease severity in patients with chronic hypersensitivity pneumonitis* [PDF]

Jornal Brasileiro de Pneumologia
Objective: Biomarkers associated with mucin 1, such as Krebs von den Lungen-6 and carbohydrate antigen (CA) 15-3, are increased in various interstitial lung diseases.
Paula Silva Gomes, Maria Raquel Soares, Maria Fernanda Munhoz Lages Marchenta, Gustavo de Souza Portes Meirelles, Rimarcs Gomes Ferreira, André Bezerra Botelho, Rafaela Boaventura Martins, Carlos Alberto de Castro Pereira   +7 more
doaj   +4 more sources

Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]

, 1967
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Okada, Shigeru, Grace, James T., Hayashi, Kenj, Kimoto, Tetsuo, Sogabe, Koichi, Shigehisa, Morio   +5 more
core   +1 more source

Melanoma-associated adhesion molecule MUC18/MCAM (CD146) and transcriptional regulator Mader in normal human CNS [PDF]

, 1998
The proteins MUC18 and Mader have been identified as markers of tumor progression in melanoma cells, MUC18, also known as MCAM (melanoma cell adhesion molecule) and as CD146 (endothelial antigen), is a cell adhesion molecule belonging to the ...
Müller, Norbert, Johnson, Judith P., Kirsch, Kathrin H., Hampel, Harald, Schwarz, Markus J., Ackenheil, Manfred, Penning, Randolph, Körschenhausen, Dirk   +7 more
core   +1 more source

Expression analysis of carbohydrate antigens in ductal carcinoma in situ of the breast by lectin histochemistry

BMC Cancer, 2008
Background The number of breast cancer patients diagnosed with ductal carcinoma in situ (DCIS) continues to grow. Laboratory and clinical data indicate that DCIS can progress to invasive disease.
Kieber-Emmons Thomas, Siegel Eric, Korourian Soheila, Monzavi-Karbassi Behjatolah   +3 more
doaj   +1 more source

Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition and adhesion [PDF]

, 2004
Carbohydrates at the cell surface have been proposed as mediators in cell-cell recognition events involved in embryogenesis, metastasis, and other proliferation processes by calcium-dependent carbohydrate to carbohydrate interactions.
Bucior, Iwona
core   +1 more source

Tumor-Associated Glycans and Immune Surveillance

Vaccines, 2013
Changes in cell surface glycosylation are a hallmark of the transition from normal to inflamed and neoplastic tissue. Tumor-associated carbohydrate antigens (TACAs) challenge our understanding of immune tolerance, while functioning as immune targets that
Anastas Pashov, Behjatolah Monzavi-Karbassi, Thomas Kieber-Emmons   +2 more
doaj   +1 more source

Tumor-associated Carbohydrate Antigens: Sialyl Le^a and T/Tn Antigens in Canine Mammary Tumors [PDF]

Veterinary Pathology, 2009
Twenty-eight canine mammary tubulopapillary carcinomas and 14 simple adenomas were studied by immunohistochemistry for the expressions of the tumor-associated carbohydrate antigens. Sialyl Lea was detected in 71.42% of the malignant and 92.84% of the benign tumors.
M, Nowak, J, Madej, P, Dziegiel, W, Lopuszynski, A, Rodo, M, Ugorski   +5 more
openaire   +2 more sources

State of the Art in CAR-T Cell Therapy for Solid Tumors: Is There a Sweeter Future?

Cells
Chimeric antigen receptor (CAR)-T cell therapy has proven to be a powerful treatment for hematological malignancies. The situation is very different in the case of solid tumors, for which no CAR-T-based therapy has yet been approved.
Beatriz Amorós-Pérez, Benigno Rivas-Pardo, Manuel Gómez del Moral, José Luis Subiza, Eduardo Martínez-Naves   +4 more
doaj   +1 more source