Results 211 to 220 of about 414,638 (260)

A New Perspective in Tumor Therapy: Targeting M2-Type Tumor-Associated Macrophages. [PDF]

open access: yesTechnol Cancer Res Treat
Zhang Q   +7 more
europepmc   +1 more source

Tumor associated macrophages and ‘NO’

Biochemical Pharmacology, 2020
Nitric oxide (NO) and its pro and anti-tumor activities are dual roles that continue to be debated in cancer biology. The cell situations in the tumor and within the tumor microenvironment also have roles involving NO. In early tumorigenic events, macrophages in the tumor microenvironment promote tumor cell death, and later are reprogramed to support ...
Niharika Nath, Khosrow Kashfi
openaire   +2 more sources

Metabolism in tumor-associated macrophages

2022
Macrophages functionally adapt to a diverse set of signals, a process that is critical for their role in maintaining or restoring tissue homeostasis. This process extends to cancer, where macrophages respond to a series of inflammatory and metabolic cues that direct a maladaptive healing response.
Jie, Li   +2 more
openaire   +2 more sources

Tumor-associated macrophages in cancers

Clinical and Translational Oncology, 2015
Tumor-associated macrophages (TAMs) are major component of leukocytic infiltrate of tumors and play important roles in progression and regression of tumors. Tumor microenvironment determines the mutual conversion between M1 and M2 macrophages. In many kinds of tumors, M2 type macrophages are of the majority in TAMs and promote tumor progression and ...
W, Hu   +5 more
openaire   +2 more sources

The origin and function of tumor-associated macrophages

Immunology Today, 1992
Tumor-associated macrophages (TAM) have a complex relationship with the neoplastic cells of the tumor. On the one hand, the two cell types produce reciprocal growth factors and may be considered to have a symbiotic relationship. On the other hand, TAM can be activated to inhibit tumor growth and destroy neoplastic cells.
Alberto Mantovani   +5 more
openaire   +3 more sources

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