Tumor-infiltrating lymphocytes in Wilms tumor [PDF]
Purpose: T-lymphocytes-infiltrating tumors (TILs) are white blood cells (CD3+) found within the tumor and are thought to indicate a T-cell-mediated specific immune response. The purpose was to evaluate the presence and the subtypes of TILs in Wilms tumor
Devendra Kumar Yadav +3 more
doaj +2 more sources
Tumor-infiltrating lymphocytes from nonrenal urological malignancies
Tumor-infiltrating lymphocytes (TIL) were isolated from 15 of 20 surgical specimens of transitional cell carcinoma of the urinary bladder, prostate cancer, testicular cancer, Wilms tumor and adrenal cancer. Expansion was carried out in four different culture conditions, each containing 1000 U/ml interleukin-2: RPMI medium with or without 20% (by volume)
Gabriel P. Haas +2 more
openalex +4 more sources
Prognostic significance of CD8 + tumor-infiltrating lymphocytes in operable breast cancer: a meta-analysis [PDF]
Background As key mediators of antitumor immunity, CD8 + tumor-infiltrating lymphocytes present antigens and initiate robust immune responses against cancer cells.
Ruijie Niu +6 more
doaj +2 more sources
Tumor-infiltrating lymphocytes for melanoma immunotherapy
Oliver Kepp +3 more
doaj +4 more sources
Significance of tumor-associated neutrophils, lymphocytes, and neutrophil-to-lymphocyte ratio in non-invasive and invasive bladder urothelial carcinoma [PDF]
Background Tumor-infiltrating neutrophils and lymphocytes play essential roles in promoting or combating various neoplasms. This study aimed to investigate the association between tumor-infiltrating neutrophils and lymphocytes and the neutrophil-to ...
Wael Abdo Hassan +5 more
doaj +1 more source
Evaluation of tumor infiltrating lymphocytes in breast carcinomas
Background: Among the parameters that have a prognostic and/or predictive significance to therapeutic response, in the case of breast carcinoma, the study of tumor-infiltrating lymphocytes in breast carcinomas is emerging.
Shovana Karki +2 more
doaj +1 more source
Tumor-infiltrating lymphocytes in colorectal carcinoma
Background: Immunotherapy has become an important modality of treatment for CRC. The cells contributing to an effective immune response are CD8+ T cells of tumor-infiltrating lymphocytes.
Shovana Karki, Sanjib Pariyar
doaj +1 more source
Tumor Infiltrating Lymphocytes in Ovarian Cancer [PDF]
Several improvements in ovarian cancer treatment have been achieved in recent years, both in surgery and in combination chemotherapy with targeting. However, ovarian tumors remain the women's cancers with highest mortality rates. In this scenario, a pivotal role has been endorsed to the immunological environment and to the immunological mechanisms ...
GASPARRI, MARIALUISA +8 more
openaire +7 more sources
CD8+ T-cell lymphocytes infiltration predict clinical outcomes in Wilms’ tumor
The abundance and location of CD8+ tumor-infiltrating lymphocytes demonstrate important facets of the anticancer immune response. CD8-expressing lymphocytes have been used in immunotherapy for multiple cancers.
Keykhosro Mardanpour +4 more
doaj +1 more source
Tumor-Infiltrating Lymphocytes in Melanoma [PDF]
Adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) is arguably the most effective treatment for patients with metastatic melanoma. With higher response rates than ipilimumab or IL-2, and longer durations of response than vemurafenib, TIL therapy carries the potential to transform current outcomes in melanoma, while also defining the way ...
Sylvia, Lee, Kim, Margolin
openaire +2 more sources

