Results 211 to 220 of about 332,900 (265)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Inhibition of protein kinase CK2 remodels the tumor immune microenvironment and sensitizes lung cancer to PD-L1 blockade. [PDF]

Exp Hematol Oncol
Zhang S, Luo L, Qu Y, Zong Y, Chen L, Li Q, Li Z, Wang J, Jie X, Xia Y, Qu B, Li J, Xu C, Zou B, Zhuang H, Meng R.   +15 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

<i>CREM</i> regulates the tumor immune microenvironment and predicts prognosis in thyroid carcinoma. [PDF]

Transl Cancer Res
Ling H, Wu G, Tang L, Hu Y.
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Multi-platform analysis of the tumor immune microenvironment associated with breast cancer subtypes. [PDF]

Oncoimmunology
Torland LA, Geisler J, Azimzade Y, Frafjord A, Røed Nilsen H, Buer L, Lømo J, Garred Ø, Tahiri A, Lyngra M, Øynebråten I, Corthay A, Sahlberg K, Kristensen V, Tekpli X.   +14 more
europepmc   +1 more source

The progress and perspective of nanomedicine in modulating the tumor immune microenvironment. [PDF]

Acta Pharm Sin B
Lin N, Tan K, Wei Y, Xie S, Liu J, Ma X.
europepmc   +1 more source

Irreversible electroporation in prostate cancer: efficacy, tumor immune microenvironment remodeling, and combination immunotherapy-a narrative review. [PDF]

Transl Androl Urol
Xiao J, Lv Z, Zhang Z, Wei H, Jiang X, Tian J.   +5 more
europepmc   +1 more source

Tumor immune microenvironment states inferred from TLS-associated immune-cell composition stratify prognosis in hepatocellular carcinoma. [PDF]

Front Immunol
Cheng C, Chen G, Zhang J, Qiu L, Li Z, Dong X, Lu C, Wu Q, Peng X, Cai Z, Zeng Y.   +10 more
europepmc   +1 more source

Hydrogel-Based Immunomodulation of Tumor Immune Microenvironment in Hepatocellular Carcinoma: Current Strategies and Future Directions. [PDF]

Int J Nanomedicine
Zhang S, Ding L, Hou T, Lin D, Qu Y.
europepmc   +1 more source