Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis [PDF]
Therapeutics and Clinical Risk Management, 2008 José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio +2 more
doaj +9 more sources
Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity [PDF]
Mediators of Inflammation, 2014 Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
doaj +7 more sources
Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series [PDF]
Journal of Medical Case Reports, 2012 Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B +2 more
doaj +4 more sources
Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases [PDF]
Neural Regeneration Research, 2022 Inflammatory processes and proinflammatory cytokines have a key role in the cellular processes of neurodegenerative diseases and are linked to the pathogenesis of functional and mental health disorders.
Fatemeh Zahedipour +4 more
doaj +3 more sources
Tumor necrosis factor alpha inhibits signaling from the insulin receptor. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1994 Insulin resistance is a common problem associated with infections and cancer and, most importantly, is the central component of non-insulin-dependent diabetes mellitus.
G. Hotamisligil +3 more
semanticscholar +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 1989 Binding of peptide hormones to surface membrane receptors leads to the transcription of specific genes within relevant target cells. How these signals are transduced to alter gene expression is largely unknown, but this mechanism probably involves a ...
Laurelee Osborn, S. Kunkel, G. Nabel
semanticscholar +2 more sources
Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]
Applied Medical Informatics, 2008 Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU +4 more
doaj +2 more sources
The concentration of tumor necrosis factor alpha in periapical lesions [PDF]
Stomatološki glasnik Srbije, 2014 Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena +6 more
doaj +4 more sources
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1992 Tumor necrosis factor alpha (TNF alpha), a primary mediator of systemic responses to sepsis and infection, can be injurious to the organism when present in excessive quantities.
K. Zee +5 more
semanticscholar +2 more sources
Integrated probability of coronary heart disease subject to the -308 tumor necrosis factor-alpha SNP: a Bayesian meta-analysis [PDF]
, 2015 We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha) gene. We use Bayesian analysis to integrate independent data sets and to infer statistically robust measurements ...
Carvalho, C. Sofia
arxiv +4 more sources