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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2021 Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You +4 more
doaj +4 more sources
Recombinant Tumor Necrosis Factor-Alpha [PDF]
Definitions, 2020 A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-alpha with antineoplastic properties.
openaire +2 more sources
Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
Mediators of Inflammation, 2014 Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
doaj +2 more sources
Tumor necrosis factor alpha in sleep regulation
Sleep Medicine Reviews, 2018 This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
Rockstrom, Matthew D +6 more
openaire +5 more sources
Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis
Therapeutics and Clinical Risk Management, 2008 José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio +2 more
doaj +5 more sources
Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease [PDF]
Current Alzheimer Research, 2017 Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Decourt, Boris +2 more
openaire +3 more sources
Kv11.1-dependent senescence activates a lethal immune response via tumor necrosis factor alpha. [PDF]
NeoplasiaSaatloo MV +4 more
europepmc +2 more sources
Tumor Necrosis Factor-Alpha (TNF- α) and Antiviral Activities of Artemisia SPP. Extracts on SARS-COV2. [PDF]
Rwanda J Med Health SciBanjo TA +15 more
europepmc +3 more sources
Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis [PDF]
Revista Brasileira de Ortopedia, 2023 Objective To analyze the serum levels of TNF-alpha and its TNF-R1 and TNF-R2 receptors in the blood of patients with low-impact fractures due to osteoporosis, comparing between genders and with healthy patients. Methods The present study was conducted
Abel Oliveira Marques Teixeira +5 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. TNF-α binds to two
Dan-in Jang +7 more
semanticscholar +1 more source