Results 1 to 10 of about 679,476 (250)

Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series [PDF]

open access: yesJournal of Medical Case Reports, 2012
Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B   +2 more
doaj   +4 more sources

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

open access: greenProceedings of the National Academy of Sciences of the United States of America, 1989
Binding of peptide hormones to surface membrane receptors leads to the transcription of specific genes within relevant target cells. How these signals are transduced to alter gene expression is largely unknown, but this mechanism probably involves a ...
L Osborn, S L Kunkel, Gary J. Nabel
openalex   +2 more sources

The concentration of tumor necrosis factor alpha in periapical lesions [PDF]

open access: yesStomatološki glasnik Srbije, 2014
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena   +6 more
doaj   +4 more sources

Single-cell multi-omics reveals the TNF-α activation threshold for Classical Monocytes by studying healthy donors and rheumatoid arthritis patients [PDF]

open access: yesFrontiers in Immunology
IntroductionTumor Necrosis Factor Alpha is a known pro-inflammatory cytokine that plays a key role in the pathogenesis of rheumatoid arthritis. Anti-cytokine therapies targeting Tumor Necrosis Factor Alpha have greatly succeeded in treating rheumatoid ...
Roman Perik-Zavodskii   +22 more
doaj   +3 more sources

Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]

open access: yesApplied Medical Informatics, 2008
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU   +4 more
doaj   +2 more sources

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

open access: yesMediators of Inflammation, 2014
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
doaj   +2 more sources

Tumor necrosis factor alpha inhibits signaling from the insulin receptor. [PDF]

open access: bronzeProceedings of the National Academy of Sciences of the United States of America, 1994
Insulin resistance is a common problem associated with infections and cancer and, most importantly, is the central component of non-insulin-dependent diabetes mellitus.
Gökhan S. Hotamışlıgil   +3 more
openalex   +2 more sources

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. [PDF]

open access: bronzeProceedings of the National Academy of Sciences of the United States of America, 1992
Tumor necrosis factor alpha (TNF alpha), a primary mediator of systemic responses to sepsis and infection, can be injurious to the organism when present in excessive quantities.
Kimberly J. Van Zee   +5 more
openalex   +2 more sources

Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis [PDF]

open access: yesRevista Brasileira de Ortopedia, 2023
Objective To analyze the serum levels of TNF-alpha and its TNF-R1 and TNF-R2 receptors in the blood of patients with low-impact fractures due to osteoporosis, comparing between genders and with healthy patients. Methods The present study was conducted
Abel Oliveira Marques Teixeira   +5 more
doaj   +1 more source

Effects of tumor necrosis factor-alpha inhibitors on lipid profiles in patients with psoriasis: a systematic review and meta-analysis [PDF]

open access: yesFrontiers in Immunology
BackgroundThere is no consensus on the effect of tumor necrosis factor-alpha (TNF-alpha) inhibitors on lipid profiles in patients with psoriasis. This study aimed to investigate the effects of TNF-alpha inhibitors on lipid profiles (triglycerides, total ...
Liang Su   +14 more
doaj   +2 more sources

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