Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis [PDF]
José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio+2 more
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Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity [PDF]
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You+4 more
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Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series [PDF]
Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B+2 more
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Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases [PDF]
Inflammatory processes and proinflammatory cytokines have a key role in the cellular processes of neurodegenerative diseases and are linked to the pathogenesis of functional and mental health disorders.
Fatemeh Zahedipour+4 more
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Binding of peptide hormones to surface membrane receptors leads to the transcription of specific genes within relevant target cells. How these signals are transduced to alter gene expression is largely unknown, but this mechanism probably involves a ...
L Osborn, S L Kunkel, Gary J. Nabel
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Tumor necrosis factor alpha inhibits signaling from the insulin receptor. [PDF]
Insulin resistance is a common problem associated with infections and cancer and, most importantly, is the central component of non-insulin-dependent diabetes mellitus.
Gökhan S. Hotamışlıgil+3 more
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Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease. [PDF]
Alzheimer's disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia.
B. Decourt, D. Lahiri, M. Sabbagh
semanticscholar +4 more sources
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
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Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU+4 more
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