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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2021 Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You +4 more
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Recombinant Tumor Necrosis Factor-Alpha [PDF]
Definitions, 2020 A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-alpha with antineoplastic properties.
semanticscholar +2 more sources
Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
Mediators of Inflammation, 2014 Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
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Tumor necrosis factor alpha in sleep regulation.
Sleep Medicine Reviews, 2017 This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
M. Rockstrom +6 more
semanticscholar +5 more sources
Tumor necrosis factor-alpha in patients with alopecia areata
Indian Journal of Dermatology, 2011 Background : Alopecia areata (AA) is a common form of localized, nonscarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis, AT), or total loss of body hair (alopecia universalis, AU).
Emina Kasumagic-Halilovic +2 more
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Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease. [PDF]
Current Alzheimer Research, 2016 Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Boris Decourt, D. Lahiri, M. Sabbagh
semanticscholar +3 more sources
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Indian Journal of Ophthalmology, 2012 Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
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Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis
Therapeutics and Clinical Risk Management, 2008 José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio +2 more
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Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase.
Journal of Lipid Research, 1994 In view of the suppressive effect of tumor necrosis factor alpha (TNF alpha) on lipoprotein lipase (LPL) and of the potential proatherogenic effects of these two macrophage secretory products, we have tested the possibility that LPL could modulate the ...
G Renier +3 more
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Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis [PDF]
Revista Brasileira de Ortopedia, 2023 Objective To analyze the serum levels of TNF-alpha and its TNF-R1 and TNF-R2 receptors in the blood of patients with low-impact fractures due to osteoporosis, comparing between genders and with healthy patients. Methods The present study was conducted
Abel Oliveira Marques Teixeira +5 more
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