Results 31 to 40 of about 1,355,842 (299)
The Role of the Tumor Stroma in Ovarian Cancer [PDF]
Frontiers in Oncology, 2014 The tumor microenvironment, consisting of stromal myofibroblasts, endothelial cells, and leukocytes, is growingly perceived to be a major contributor to the pathogenesis and disease progression in practically all cancer types. Stromal myofibroblasts produce angiogenic factors, proteases, growth factors, immune response-modulating proteins, anti ...
Davidson, Ben +2 more
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Türk Patoloji Dergisi, 2023 Objective: Tumor border configuration, tumor budding and tumor stroma ratio are reliable histopathological parameters that play a central role in the invasion-metastasis cascade.
Lamia Sabry ABOELNASR +3 more
doaj +1 more source
The last tenascin : insights on tenascin-W functions and regulation [PDF]
, 2012 Over the last decade, it became clear that the tumor stroma plays an active role in the process of tumor progression, by interacting with the transformed cells and providing a permissive microenvironment for malignant growth.
Martina, Enrico
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Tumor-stroma relationships [PDF]
Cell Cycle, 2012 Cancer is characterized by somatic mutations that provide a growth and survival advantage. The mutations are a function of chance because of the random nature of mutagenesis. However, the biology in the tumor cells drives the selection of mutations that are advantageous to the cancer.1 In addition, the tumor environment exerts a selective pressure on ...
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médecine/sciences, 2014 Les carcinomes sont composes, d’une part, de cellules epitheliales malignes et, d’autre part, du microenvironnement tumoral, encore appele stroma tumoral. Cette revue, non exhaustive, se focalisera sur les evenements cellulaires et moleculaires cles impliquant les cancer-associated fibroblasts (CAF) et la matrice extracellulaire (MEC) dans le ...
Émilie Buache, Marie-Christine Rio
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Cells, 2019 Small extracellular vesicles (small EVs) are commonly released by all cells, and are found in all body fluids. They are implicated in cell to cell short- and long-distance communication through the transfer of genetic material and proteins, as well as ...
Ernesto Gargiulo +2 more
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Journal of Mid-Life Health, 2023 Background: Ovarian cancer is the 8th most common cancer in women worldwide. Tumor budding is defined as a type of invasive growth in carcinomas with either a single tumor cell or a cluster of up to four cells at the invasive tumor front and is ...
Sana Ahuja, Sufian Zaheer, Sunil Ranga
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Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. [PDF]
, 1993 associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging.
Nass, Ralf +3 more
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Tumor-stroma derived gene expression patterns as prognosticators in breast cancer [PDF]
, 2010 The stroma, which embeds epithelial cells, plays a major role in the shaping and physiological regulation of animal organs such as the breast. Aberrant functioning of the stroma was found to support tumorigenesis and cancer progression.
Rajski, Michal
core +1 more source
Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival. [PDF]
PLoS ONE, 2010 BACKGROUND: The identification of new prognostic markers for prostate cancer is highly warranted, since it is difficult to identify patients requiring curative treatment.
Christina Hägglöf +6 more
doaj +1 more source