Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169+ cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, factors regulating CD169+
Prashant V. Shinde +28 more
semanticscholar +1 more source
IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source
Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]
INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo +5 more
core +1 more source
Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]
Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines +5 more
core +1 more source
Initial Stages of Mammary Tumor Virus Infection Are Superantigen Independent [PDF]
Abstract Exogenous mouse mammary tumor virus (MMTV) is transmitted via the milk from infected mothers to newborn pups. Efficient MMTV transmission is dependent on proliferation of T cells with particular TCR β-chains, which occurs upon recognition of virally encoded superantigen (SAg) bound to MHC class II molecules.
Pobezinskaya, Y +2 more
openaire +2 more sources
Prevalence and Viral Load Determination of BK Polyomavirus among Iranian Patients with Brain Tumors
Background: Due to persistent infections of human central nervous system (CNS), polyomaviruses have been identified as one of the risk factors for brain tumor development.
Saghar Saber Amoli +6 more
doaj
The Role of HLA-G in Human Papillomavirus Infections and Cervical Carcinogenesis
Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low polymorphism frequency, restricted tissue distribution and immunoinhibitory property.
Hui-Hui Xu, Wei-Hua Yan, Aifen Lin
doaj +1 more source
Examining the role of EGR1 during viral infections
Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array of stimuli such as exposure to growth factors, cytokines, apoptosis, and
Caitlin M. Woodson +3 more
doaj +1 more source
Diagnosis and Neurosurgical Management of Cerebral Nocardiosis
Primary Nocardia infections are uncommon gram-positive bacterial infections caused by aerobic actinomycetes and are typically regarded as opportunistic infections (only one-third of infected patients are immunocompetent).
Carley Karam, Abdolreza Siadati
doaj +1 more source
Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection
Preferential killing of transformed cells, while keeping normal cells and organs unharmed, is the main goal of cancer gene therapy. Genetically engineered trackable markers and imaging reporters enable noninvasive monitoring of transduction efficiency and pharmacokinetics of anticancer virotherapeutics.
Iankov, Ianko D +4 more
openaire +2 more sources

