Results 31 to 40 of about 209,274 (278)

Power and limitations of electrophoretic separations in proteomics strategies [PDF]

open access: yes, 2009
Proteomics can be defined as the large-scale analysis of proteins. Due to the complexity of biological systems, it is required to concatenate various separation techniques prior to mass spectrometry.
Aebersold   +225 more
core   +4 more sources

Automatic selection of two-dimensional electrophoresis gel with least geometric distortions

open access: yesMokslas: Lietuvos Ateitis, 2010
The paper presents an algorithm for automated selection of the highest quality two-dimensional gel electrophoresis image. The quality criterion is the amount of vertical geometric distortions of the gel.
Dalius Matuzevičius
doaj   +1 more source

Proteome Analysis of Pyloric Ceca: A Methodology for Fish Feed Development? [PDF]

open access: yes, 2012
Changing the protein source of fish feed from fish meal to alternative sources of protein will affect traits such as fish growth, quality, and feed utilization.
Jessen, Flemming   +4 more
core   +1 more source

A Routine ‘Top-Down’ Approach to Analysis of the Human Serum Proteome

open access: yesProteomes, 2017
Serum provides a rich source of potential biomarker proteoforms. One of the major obstacles in analysing serum proteomes is detecting lower abundance proteins owing to the presence of hyper-abundant species (e.g., serum albumin and immunoglobulins ...
Arlene M. D’Silva   +2 more
doaj   +1 more source

Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research

open access: yesBiology, 2013
In this article, we illustrate the application of difference in-gel electrophoresis for the proteomic analysis of dystrophic skeletal muscle. The mdx diaphragm was used as a tissue model of dystrophinopathy.
Steven Carberry   +3 more
doaj   +1 more source

Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]

open access: yes, 2006
Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille   +3 more
core   +4 more sources

Comparative 2-DE protein analysis in a 3-D geometry gel

open access: yesBioTechniques, 2007
Two-dimensional gel electrophoresis (2-DE) separation has not been considered suitable for large-scale comparative protein expression studies due to its limited throughput.
Robert Ventzki   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Protein profile analysis of Malaysian snake venoms by two-dimensional gel electrophoresis

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2010
Snake venoms comprise a highly complex mixture of proteins, which requires for their characterization the use of versatile two-dimensional electrophoresis techniques.
J Vejayan   +4 more
doaj   +1 more source

Dataset of Two-Dimensional Gel Electrophoresis Images of Acute Myeloid Leukemia Patients before and after Induction Therapy

open access: yesData, 2021
Acute myeloid leukemia (AML) is a malignant disorder of the hematopoietic stem and progenitor cells, which results in the build-up of immature blasts in the bone marrow and eventually in the peripheral blood of affected patients.
Juan E. Urrea   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy