Results 11 to 20 of about 2,373,806 (358)
Inflammasomes and Type 1 Diabetes [PDF]
Frontiers in Immunology, 2021 Microbiota have been identified as an important modulator of susceptibility in the development of Type 1 diabetes in both animal models and humans. Collectively these studies highlight the association of the microbiota composition with genetic risk ...
James Alexander Pearson +2 more
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Indian Journal of Endocrinology and Metabolism, 2015 Various data on type 1 diabetes mellitus (T1DM) have showed that the incidence of T1DM peaks at puberty. However, diabetes control and complications could be adversely affected by the physiological changes of puberty.
Subhankar Chowdhury
doaj +3 more sources
Empagliflozin in type 1 diabetes
Diabetes, Metabolic Syndrome and Obesity, 2019 Chantal Mathieu, Laura Van Den Mooter, Bert EeckhoutEndocrinology, UZ Gasthuisberg, Leuven 3000, BelgiumCorrespondence: Chantal MathieuEndocrinology, UZ Gasthuisberg, Herestraat 49, Leuven 3000, BelgiumEmail chantal.mathieu@uzleuven.beAbstract: There is ...
Mathieu C, Van Den Mooter L, Eeckhout B
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The Lancet, 2023 Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced knowledge related to the pathophysiology of the disease, including interactions between genetic, immune, and environmental contributions, and major strides in treatment and ...
Quattrin, Teresa +2 more
openaire +3 more sources
The Lancet, 2014 Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge ...
Mark A, Atkinson +2 more
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Clinical Chemistry, 1999 AbstractType 1 (insulin-dependent) diabetes occurs worldwide and can appear at any age. The genetic susceptibility is strongly associated with HLA-DQ and DR on chromosome 6, but genetic factors on other chromosomes such as the insulin gene on chromosome 11 and the cytotoxic T-lymphocyte antigen gene on chromosome 2 may modulate disease risk.
openaire +2 more sources
Residual C-peptide secretion and hypoglycemia awareness in people with type 1 diabetes
BMJ Open Diabetes Research & Care, 2021 Introduction This study aimed to assess the association between fasting serum C-peptide levels and the presence of impaired awareness of hypoglycemia (IAH) in people with type 1 diabetes.Research design and methods We performed a cross-sectional study ...
Giesje Nefs +9 more
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Cell Therapy for Type 1 Diabetes [PDF]
, 2014 Acknowledgements The work described in this review was supported by a grant from the MRC. K.R.M. is supported by a fellowship from the Scottish Translational Medicines and Therapeutics Initiative through the Wellcome Trust.Peer reviewedPublisher ...
Docherty, H. M. +3 more
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Antigen-Specific Treg Therapy in Type 1 Diabetes – Challenges and Opportunities
Frontiers in Immunology, 2021 Regulatory T cells (Tregs) are key mediators of peripheral self-tolerance and alterations in their frequencies, stability, and function have been linked to autoimmunity.
Isabelle Serr +7 more
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miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes
Frontiers in Endocrinology, 2020 The important role of microRNAs as major modulators of various physiological processes, including immune regulation and homeostasis, has been increasingly recognized.
Martin G. Scherm +4 more
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