Results 11 to 20 of about 2,183,210 (336)

Advances in Human Immune System Mouse Models for Personalized Treg-Based Immunotherapies

Frontiers in Immunology, 2021
Immunodeficient mice engrafted with a functional human immune system [Human immune system (HIS) mice] have paved the way to major advances for personalized medicine and translation of immune-based therapies.
Isabelle Serr, Isabelle Serr, Maria Kral, Maria Kral, Martin G. Scherm, Martin G. Scherm, Carolin Daniel, Carolin Daniel, Carolin Daniel   +8 more
doaj   +1 more source

Differences in lipid and blood pressure measurements between individuals with type 1 diabetes and the general population: a cross-sectional study

BMJ Open, 2023
Objectives Cardiovascular disease (CVD) is a precarious complication of type 1 diabetes (T1D). Alongside glycaemic control, lipid and blood pressure (BP) management are essential for the prevention of CVD.
Bruce H R Wolffenbuttel, Melanie M van der Klauw, Henk-Jan Aanstoot, Rita Delphine Maiko Varkevisser, Dick Mul   +4 more
doaj   +1 more source

Type 1 Diabetes [PDF]

JAMA, 2003
Diabetes is a complex metabolic disorder diagnosed on the basis of hyperglycemia. Diagnostic criteria for the disorder are periodically revised (1). Diabetes may be classified mainly into types 1 and 2 based on the etiology and severity of insulin deficiency (1).
Yogish C. Kudva, Robert A. Rizza, Rita Basu   +2 more
openaire   +8 more sources

Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT). [PDF]

, 2011
BACKGROUND: The prognosis for young people diagnosed with diabetes during childhood remains poor and this is mainly related to the long-term risk of developing vascular complications.Microalbuminuria identifies subjects at risk for diabetic nephropathy ...
Adolescent type 1 Diabetes cardio-renal Intervention Trial Research Group
core   +1 more source

Latent Autoimmune Diabetes in Adults in the United Arab Emirates: Clinical Features and Factors Related to Insulin-Requirement [PDF]

, 2015
AIMS: To describe and to characterize clinical features of latent autoimmune diabetes in adults (LADA) compared to type 1 and type 2 diabetes in the UAE.
Al Tikriti, Alia, Barakat, Maha T., Buzzetti, Raffaella, Lessan, Nader, Maddaloni, Ernesto, Pozzilli, Paolo   +5 more
core   +7 more sources

Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

Frontiers in Immunology, 2021
Type 1 diabetes is an immune-driven disease, where the insulin-producing beta cells from the pancreatic islets of Langerhans becomes target of immune-mediated destruction.
Caroline Frørup, Caroline Frørup, Aashiq H. Mirza, Aashiq H. Mirza, Reza Yarani, Lotte B. Nielsen, Elisabeth R. Mathiesen, Elisabeth R. Mathiesen, Peter Damm, Peter Damm, Peter Damm, Jens Svare, Christian Engelbrekt, Joachim Størling, Joachim Størling, Jesper Johannesen, Jesper Johannesen, Henrik B. Mortensen, Henrik B. Mortensen, Flemming Pociot, Flemming Pociot, Flemming Pociot, Simranjeet Kaur   +22 more
doaj   +1 more source

Residual C-peptide secretion and hypoglycemia awareness in people with type 1 diabetes

BMJ Open Diabetes Research & Care, 2021
Introduction This study aimed to assess the association between fasting serum C-peptide levels and the presence of impaired awareness of hypoglycemia (IAH) in people with type 1 diabetes.Research design and methods We performed a cross-sectional study ...
Giesje Nefs, Bruce H R Wolffenbuttel, Peter R van Dijk, Petronella H Geelhoed-Duijvestijn, Henk-Jan Aanstoot, Martine J Wellens, Charlotte E Vollenbrock, Pim Dekker, Lianne S M Boesten, Martine M C de Vries-Velraeds   +9 more
doaj   +1 more source

Ketoacidosis in type 2 diabetes- is it type 1 and ½ diabetes? [PDF]

BMJ Case Reports, 2011
A 64-year-old female with a background of type 2 diabetes became acutely unwell after being transferred from insulin to liraglutide, which is one of the new glucagon like peptide 1 analogues. On assessment in accident and emergency, she was diagnosed with diabetic ketoacidosis and pancreatits. Glutamic acid decarboxylase antibodies were positive at 45 (
Sathis Kumar, Debbie Gooderick, Umesh Dashora   +2 more
openaire   +2 more sources

Type 1 diabetes in children [PDF]

, 2013
Many children are not diagnosed early enough.
Kime, NH
core   +1 more source

Antigen-Specific Treg Therapy in Type 1 Diabetes – Challenges and Opportunities

Frontiers in Immunology, 2021
Regulatory T cells (Tregs) are key mediators of peripheral self-tolerance and alterations in their frequencies, stability, and function have been linked to autoimmunity.
Isabelle Serr, Isabelle Serr, Felix Drost, Benjamin Schubert, Benjamin Schubert, Carolin Daniel, Carolin Daniel, Carolin Daniel   +7 more
doaj   +1 more source