Results 21 to 30 of about 4,565,322 (357)
Ketoacidosis in type 2 diabetes- is it type 1 and ½ diabetes? [PDF]
BMJ Case Reports, 2011 A 64-year-old female with a background of type 2 diabetes became acutely unwell after being transferred from insulin to liraglutide, which is one of the new glucagon like peptide 1 analogues. On assessment in accident and emergency, she was diagnosed with diabetic ketoacidosis and pancreatits. Glutamic acid decarboxylase antibodies were positive at 45 (
Sathis Kumar +2 more
openaire +2 more sources
State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018
Diabetes Technology & Therapeutics, 2019 Objective: To provide a snapshot of the profile of adults and youth with type 1 diabetes (T1D) in the United States and assessment of longitudinal changes in T1D management and clinical outcomes in the T1D Exchange registry.
N. Foster +11 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Type 1 diabetes is an immune-driven disease, where the insulin-producing beta cells from the pancreatic islets of Langerhans becomes target of immune-mediated destruction.
Caroline Frørup +22 more
doaj +1 more source
Prevention of Type 1 Diabetes [PDF]
Pediatric Clinics of North America, 2009 Prevention of loss of beta cells in type 1 diabetes is a major goal of current research. Knowledge of the genetic susceptibility, increasing ability to predict who may be at risk, recognition of the potential clinical impact of residual insulin secretion after diagnosis, and development of new immunomodulatory agents have supported an increasing number
Denis Daneman, Diane K. Wherrett
openaire +5 more sources
Residual C-peptide secretion and hypoglycemia awareness in people with type 1 diabetes
BMJ Open Diabetes Research & Care, 2021 Introduction This study aimed to assess the association between fasting serum C-peptide levels and the presence of impaired awareness of hypoglycemia (IAH) in people with type 1 diabetes.Research design and methods We performed a cross-sectional study ...
Giesje Nefs +9 more
doaj +1 more source
New-Onset Type 1 Diabetes in Children During COVID-19: Multicenter Regional Findings in the U.K.
Diabetes Care, 2020 Data on new-onset type 1 diabetes during the coronavirus disease 2019 (COVID-19) pandemic, particularly in children, are limited. A recent U.S. multicenter study reported outcomes in 64 adults and children with type 1 diabetes, and confirmed or suspected
R. Unsworth +8 more
semanticscholar +1 more source
Antigen-Specific Treg Therapy in Type 1 Diabetes – Challenges and Opportunities
Frontiers in Immunology, 2021 Regulatory T cells (Tregs) are key mediators of peripheral self-tolerance and alterations in their frequencies, stability, and function have been linked to autoimmunity.
Isabelle Serr +7 more
doaj +1 more source
miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes
Frontiers in Endocrinology, 2020 The important role of microRNAs as major modulators of various physiological processes, including immune regulation and homeostasis, has been increasingly recognized.
Martin G. Scherm +4 more
doaj +1 more source
A journey toward an open data culture through transformation of shared data into a data resource
Data & Policy, 2022 The transition to open data practices is straightforward albeit surprisingly challenging to implement largely due to cultural and policy issues. A general data sharing framework is presented along with two case studies that highlight these challenges and
Scott D. Kahn, Anne Koralova
doaj +1 more source
Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)
Nature Reviews Endocrinology, 2020 Type 1 diabetes mellitus is believed to result from destruction of the insulin-producing β-cells in pancreatic islets that is mediated by autoimmune mechanisms. The classic view is that autoreactive T cells mistakenly destroy healthy (‘innocent’) β-cells.
B. Roep +3 more
semanticscholar +1 more source