Results 41 to 50 of about 2,420,770 (348)
Molecular MetabolismObjective: In autoimmune Type 1 Diabetes (T1D), aberrant immune activation promotes regulatory T cell (Treg) impairments thereby boosting progression of islet autoimmunity.
Hannah Hipp +14 more
doaj +1 more source
Collagenase Isoforms for Pancreas Digestion
Cell Transplantation, 2009 The available information concerning the characteristics and composition of collagenase batches, which are effective in the digestion of human pancreas for islet transplants, is scarce and incomplete.
Federico Bertuzzi +7 more
doaj +1 more source
Type 1 diabetes and cardiovascular disease [PDF]
, 2013 The presence of cardiovascular disease (CVD) in Type 1 diabetes largely impairs life expectancy. Hyperglycemia leading to an increase in oxidative stress is considered to be the key pathophysiological factor of both micro- and macrovascular complications.
Cappuccio, Francesco +5 more
core +2 more sources
Diabetic nephropathy in type 1 diabetes
Minerva Medica, 2018 Diabetic nephropathy (DN) also named diabetic kidney disease (DN) is one of the leading causes of mortality in people with diabetes. The aim of this review is to update the medical literature, the theories behind its early natural history, the pathways of its pathogenesis, its diagnosis and treatment.
Papadopoulou-Marketou, N. +5 more
openaire +3 more sources
Cell Transplantation, 2016 Type 1 diabetes (T1D) is characterized by destruction of glucose-responsive insulin-producing pancreatic β-cells and exhibits immune infiltration of pancreatic islets, where CD8 lymphocytes are most prominent.
Tobias Boettler +6 more
doaj +1 more source
Does Type 1 Diabetes Affect Male Infertility: Type 1 Diabetes Exchange Registry-Based Analysis
Société Internationale d’Urologie Journal, 2021 IntroductionThe prevalence of type 1 diabetes (T1D) has been increasing over the last few decades and is commonly believed to negatively impact male fertility.
Omer A. Raheem, Marah C. Hehemann, Marc J. Rogers, Judy N. Fustok, Irl B. Hirsch, Thomas J. Walsh
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine +10 more
wiley +1 more source
BMJ, 2011 Type 1 diabetes in childhood is one of the commoner long term conditions of childhood. It is treated by specialist teams in secondary care using increasingly intensive insulin regimens, but the onset is generally diagnosed by primary care physicians, sometimes later than is ideal.
Ali, K, Harnden, A, Edge, J
openaire +5 more sources
Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li +6 more
wiley +1 more source
Bioactive MaterialsInflammatory bowel disorders (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract (GIT). They pose significant treatment challenges due to their complex etiology.
George Chigozie Njoku +5 more
doaj +1 more source