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Codesigned Shared Decision-Making Diabetes Management Plan Tool for Adolescents With Type 1 Diabetes Mellitus and Their Parents: Prototype Development and Pilot Test [PDF]
, 2018 Background: Adolescents with type 1 diabetes mellitus have difficulty achieving optimal glycemic control, partly due to competing priorities that interfere with diabetes self-care.
Carroll, Aaron E. +7 more
core +1 more source
Type 1 Diabetes at a Crossroads! [PDF]
Diabetes Care, 2015 “Be at a crossroads”: to be at a stage in your life when you have to make a very important decision (1). Type 1 diabetes at a crossroads? What does that really mean? It cannot mean that progress has not been made! Indeed, in the field of diabetes, reporting of new information is clearly outpacing our ability to incorporate new findings into clinical ...
William V. Tamborlane +2 more
openaire +3 more sources
Latent Autoimmune Diabetes in Adults in the United Arab Emirates: Clinical Features and Factors Related to Insulin-Requirement [PDF]
, 2015 AIMS: To describe and to characterize clinical features of latent autoimmune diabetes in adults (LADA) compared to type 1 and type 2 diabetes in the UAE.
Al Tikriti, Alia +5 more
core +3 more sources
Neutrophils in type 1 diabetes [PDF]
Journal of Diabetes Investigation, 2016 AbstractType 1 diabetes is an autoimmune disease that afflicts millions of people worldwide. It occurs as the consequence of destruction of insulin‐producing pancreatic β‐cells triggered by genetic and environmental factors. The initiation and progression of the disease involves a complicated interaction between β‐cells and immune cells of both innate ...
Juan Huang +3 more
openaire +2 more sources
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes [PDF]
, 2019 OBJECTIVE: Abnormally elevated proinsulin secretion has been reported in type 2 and early type 1 diabetes when significant C-peptide is present. We questioned whether individuals with long-standing type 1 diabetes and low or absent C-peptide secretory
Arvan, Peter +22 more
core +1 more source
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes
Nature Communications, 2019 miRNA142-3p and Tet2 are separately known to regulate Treg. Here the authors show that miRNA142-3p targets Tet2 and by this opposes Treg differentiation in autoimmune diabetes.
Martin G. Scherm +11 more
doaj +1 more source
A new perspective on metformin therapy in type 1 diabetes [PDF]
, 2017 Metformin is quite frequently used off-label in type 1 diabetes to limit insulin dose requirement. Guidelines recommend that it can improve glucose control in those who are overweight and obese but evidence in support of this is limited.
Boyle, James G. +2 more
core +1 more source
Cell Transplantation, 2016 Type 1 diabetes (T1D) is characterized by destruction of glucose-responsive insulin-producing pancreatic β-cells and exhibits immune infiltration of pancreatic islets, where CD8 lymphocytes are most prominent.
Tobias Boettler +6 more
doaj +1 more source
Symptom based Hierarchical Classification of Diabetes and Thyroid disorders using Fuzzy Cognitive Maps [PDF]
arXiv, 2021 Fuzzy Cognitive Maps (FCMs) are soft computing technique that follows an approach similar to human reasoning and human decision-making process, making them a valuable modeling and simulation methodology. Medical Decision Systems are complex systems consisting of many factors that may be complementary, contradictory, and competitive; these factors ...
arxiv
Collagenase Isoforms for Pancreas Digestion
Cell Transplantation, 2009 The available information concerning the characteristics and composition of collagenase batches, which are effective in the digestion of human pancreas for islet transplants, is scarce and incomplete.
Federico Bertuzzi +7 more
doaj +1 more source