Results 11 to 20 of about 60,244 (228)
Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili. [PDF]
Proc Natl Acad Sci U S AGram-negative bacteria produce chaperone–usher pathway pili, which are extracellular protein fibers tipped with an adhesive protein that binds to a receptor with stereochemical specificity to determine host and tissue tropism. The outer-membrane usher protein, together with a periplasmic chaperone, assembles thousands of pilin subunits ...
Bitter RM +6 more
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Dissociation and reassembly of Escherichia coli type 1 pili [PDF]
Journal of Bacteriology, 1981 Escherichia coli type 1 pili, which mediate the mannose-sensitive adherence of the bacterium to eucaryotic cells, are comprised of very stable arrays of pilin protein subunits (molecular weight, approximately 17,000). Previous methods for the dissociation of pili caused their irreversible denaturation. We have found that incubation of pili in saturated
Y, Eshdat, F J, Silverblatt, N, Sharon
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Characterization of type 1 pili of Salmonella typhimurium LT2 [PDF]
Journal of Bacteriology, 1980 Type 1 pili from Salmonella typhimurium LT2 were purified and characterized. The pilus filaments were 6 nm in diameter and over 1 microns long. Estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the molecular weight of the pilin was 21,000. The isoelectric point of the filament was 4.1.
T K, Korhonen +3 more
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Molecular mechanism of bacterial type 1 and P pili assembly [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2015 The formation of adhesive surface structures called pili or fimbriae (‘bacterial hair’) is an important contributor towards bacterial pathogenicity and persistence. To fight often chronic or recurrent bacterial infections such as urinary tract infections, it is necessary to understand the molecular mechanism of the nanomachines assembling such pili ...
Andreas, Busch +2 more
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Association of type 1 pili with the ability of livers to clear Salmonella typhimurium [PDF]
Infection and Immunity, 1982 The role of type 1 pili in the adherence of Salmonella typhimurium strain SR-11 to hepatic sinusoidal cells was investigated. An average of 66.7% of piliated organisms was cleared by perfused livers on a single pass. Mannose and alpha-methyl-D-mannoside inhibited such trapping in a dose-dependent manner. Preincubation of the bacteria, but not the liver,
R D, Leunk, R J, Moon
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A Small Non-Coding RNA Modulates Expression of Pilus-1 Type in Streptococcus pneumoniae
Microorganisms, 2021 Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, and about 30% of the pneumococcal clinical isolates show type I pili-like structures.
Paloma Acebo +6 more
doaj +1 more source
Frequency among Enterobacteriaceae of the DNA sequences encoding type 1 pili [PDF]
Journal of Bacteriology, 1985 Type 1 pili, characterized by mannose-inhibitable agglutination of fowl or guinea pig erythrocytes, have been found throughout the family Enterobacteriaceae. A radiolabeled probe was prepared from a restriction endonuclease-digested fragment of the Escherichia coli pil operon and used to detect homologous DNA sequences in 236 bacteria representing 11 ...
K, Buchanan +3 more
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Distribution of type 1 and P pili on uropathogenic Escherichia coli O6 [PDF]
Infection and Immunity, 1987 The distribution of type 1 and P pili on individual cells of an O6 uropathogenic Escherichia coli strain, 6260, was determined immunologically with pilus-specific monoclonal antibodies by indirect immunofluorescence and immunogold electron microscopy.
R M, Gander, V L, Thomas
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A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis.
PLoS Pathogens, 2021 Type 1 pili have long been considered the major virulence factor enabling colonization of the urinary bladder by uropathogenic Escherichia coli (UPEC). The molecular pathogenesis of pyelonephritis is less well characterized, due to previous limitations ...
Lisa K McLellan +12 more
doaj +1 more source
High levels of cyclic di-GMP in Klebsiella pneumoniae attenuate virulence in the lung [PDF]
, 2018 The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant ...
Hunstad, David A +2 more
core +2 more sources