Results 1 to 10 of about 16,650 (135)
Enhancing the Efficacy of Melanoma Treatment: The In Vitro Chemosensitising Impact of Vipera ammodytes Venom on Human Melanoma Cell Lines [PDF]
ToxinsResearch on viper venom has expanded into diverse medical applications, including cancer treatment. This study investigates the potential of Vipera ammodytes venom in oncology, evaluating its cytotoxicity and chemosensitising effects on malignant ...
Giovanni Paolino +10 more
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Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin [PDF]
Cellular & Molecular Biology LettersThe skin is a barrier that protects the human body against environmental factors (physical, including solar radiation, chemicals, and pathogens). The integrity and, consequently, the effective metabolic activity of skin cells is ensured by the cell ...
Michał Biernacki +1 more
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Virulence factors in Pseudomonas aeruginosa: The arms race between bacteria and humans [PDF]
Microbes and Infectious Diseases, 2023 Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative, motile bacillus that can grow at 42°C as well as 37°C in aerobic circumstances. It also tests positive for oxidase and catalase enzymes.The bacteria may be found in a variety of habitats ...
Falah AL-Khikani
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background Snake venoms are complex mixtures of toxic proteins or peptides encoded by various gene families that function synergistically to incapacitate prey.
Xuekui Nie +7 more
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Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]
PeerJ, 2014 Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma +3 more
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Molecules, 2023 Secreted phospholipases A2 are snake-venom proteins with many biological activities, notably anti-tumor activity. Phospholipases from the same snake type but different geographical locations have shown similar biochemical and biological activities with ...
Mona Alonazi +6 more
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Metabolites, 2022 While the roles of a few specific lipids in plant freezing tolerance are understood, the effect of many plant lipids remains to be determined. Acclimation of plants to non-freezing cold before exposure to freezing temperatures improves the outcome of ...
Hieu Sy Vu +17 more
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Molecules, 2023 One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family of enzymes termed phospholipases: phospholipase A2 ...
Cándido Ortiz-Placín +3 more
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Modification of phosphoinositides by the Shigella effector IpgD during host cell infection
Frontiers in Cellular and Infection Microbiology, 2022 Shigella, the causative agent of bacillary dysentery, subvert cytoskeletal and trafficking processes to invade and replicate in epithelial cells using an arsenal of bacterial effectors translocated through a type III secretion system. Here, we review the
Guy Tran Van Nhieu +2 more
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Two Different Phospholipases C, Isc1 and Pgc1, Cooperate To Regulate Mitochondrial Function
Microbiology Spectrum, 2022 The absence of Isc1, the yeast homologue of mammalian neutral sphingomyelinase type 2, leads to severe mitochondrial dysfunction. We show that the deletion of another type C phospholipase, the phosphatidylglycerol (PG)-specific phospholipase Pgc1 ...
Maria Balazova +6 more
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