Results 151 to 160 of about 533,494 (308)

Systemic lupus erythematosus and cardiovascular disease

Journal of Internal Medicine, Volume 293, Issue 1, Page 48-62, January 2023., 2023
Abstract The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment and care, but cardiovascular disease (CVD) still remains an important clinical problem, since the risk of CVD in SLE is much higher than among controls.
Johan Frostegård
wiley   +1 more source

Protein Kinase A–Dependent Stimulation of Rat Type II Secreted Phospholipase A ₂ Gene Transcription Involves C/EBP-β and -δ in Vascular Smooth Muscle Cells

, 2000
Cyril Couturier, Valérie Antonio, Arthur Brouillet, G. Béréziat, Michel Raymondjean, Marise Andréani   +5 more
openalex   +1 more source

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Phospholipase C-related but Catalytically Inactive Protein Is Required for Insulin-induced Cell Surface Expression of γ-Aminobutyric Acid Type A Receptors [PDF]

, 2009
Makoto Fujii, Takashi Kanematsu, Hitoshi Ishibashi, Kiyoko Fukami, Tadaomi Takenawa, Keiichi I. Nakayama, Stephen J. Moss, Junichi Nabekura, Masato Hirata   +8 more
openalex   +1 more source

Microglial Drivers of Alzheimer's Disease Pathology: An Evolution of Diverse Participating States

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Microglia, the resident immune‐competent cells of the brain, become dysfunctional in Alzheimer's disease (AD), and their aberrant immune responses contribute to the accumulation of pathological proteins and neuronal injury. Genetic studies implicate microglia in the development of AD, prompting interest in developing immunomodulatory therapies
Madison K. Kuhn, Elizabeth A. Proctor
wiley   +1 more source

Representation type of higher level cyclotomic quiver Hecke algebras in affine type C [PDF]

arXiv
We determine representation type of cyclotomic quiver Hecke algebras whose Lie type are affine type C. When they are tame, we give their basic algebras in explicit form under the assumption $\text{ch}\ \mathbb{k}\ne2$, which we require cellularity to be Morita invariant.
arxiv  

Biohybrid Microrobots Based on Jellyfish Stinging Capsules and Janus Particles for In Vitro Deep‐Tissue Drug Penetration

Small Science, EarlyView.
This study introduces a biohybrid microrobot utilizing jellyfish‐stinging capsules as nanoinjectors, integrated onto Janus particles. Controlled by magnetic and electric fields, these microrobots achieve deep tissue penetration and precise drug delivery.
Sinwook Park, Noga Barak, Tamar Lotan, Gilad Yossifon   +3 more
wiley   +1 more source

Activation of the phospholipase C pathway by ATP is mediated exclusively through nucleotide type P₂‐purinoceptors in C2C12 myotubes [PDF]

, 1993
Robert H. Henning, Marry Duin, Adriaan den Hertog, Adriaan Nelemans   +3 more
openalex   +1 more source

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

Small Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu, Wenjun Xue, Guanchao Mao, Zhipeng Pei, Jingjing Li, Mingxue Sun, Xinkang Zhang, Shanshan Zhang, Songling Li, Jinfeng Cen, Kai Xiao, Ying Lu, Qingqiang Xu   +12 more
wiley   +1 more source

Integrating construction and spatial imaging of organoid for tumor metabolic heterogeneity and interactions

VIEW, EarlyView.
Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo, Zhaohua Xia, Jiaxin Wang, Xiaoling Yu, Chuanyue Wu, Qian Luo, Chao Zhao   +6 more
wiley   +1 more source