Results 211 to 220 of about 316,467 (262)

Type I-interferon β induces a strong anti-tumour response in bladder cancer cells. [PDF]

J Cancer Res Clin Oncol
Hesse M, Iltzsche M, Nahhas D, Thomas C, Füssel S, Kind B.   +5 more
europepmc   +1 more source

TRIM21 regulation of IRF-mediated type I interferon signaling in systemic autoimmune diseases. [PDF]

Front Immunol
Panlu K, Wang Y, Zhu X, Lin Z, Fang T, Yao X, Xie Z, Wang X.   +7 more
europepmc   +1 more source

Regulatory dynamics of <i>IFI44L</i> in systemic lupus erythematosus: the interplay of type I interferon and c-Jun. [PDF]

Lupus Sci Med
Wang Y, Yang M, Ma H, Ma X, Huo Z, Ma Z, Dang J.   +6 more
europepmc   +1 more source

Type I interferon signaling is required for resistance to primary influenza virus infection and vaccine-induced long-term immunity. [PDF]

J Virol
Kim K-H, Hwang HS, Pal SS, Tien Le CT, Grovenstein P, Yeasmin M, Song JM, Kwon Y-M, Wang B, Kang S-M.   +9 more
europepmc   +1 more source

HCMV encoded UL84 hijacks FHL2 to suppress type I interferon production and enhance viral replication. [PDF]

PLoS Pathog
Li R, Xia S, Li X, Zeng Y, Wang T, Xia C, Li H, Chen J.   +7 more
europepmc   +1 more source

Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells

Holt JH, Enriquez-Gasca R, Wilson RP, Bochukova EG, Maillard PV, Rowe HM.   +5 more
europepmc   +1 more source

A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages.

Immunity
Dunphy G, Adán-Barrientos I, Fernández-Delgado I, Villarroya-Beltri C, Heras-Murillo I, Moya-Ruiz E, Sánchez-Álvarez M, Jarit-Cabanillas A, Del Pozo MA, Guerra S, Sánchez-Madrid F, Sancho D.   +11 more
europepmc   +1 more source

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Type I Interferons in Autoimmunity

Journal of Investigative Dermatology, 2022
Dysregulated IFN-1 responses play crucial roles in the development of multiple forms of autoimmunity. Many patients with lupus, systemic sclerosis, Sjogren's syndrome, and dermatomyositis demonstrate enhanced IFN-1 signaling. IFN-1 excess is associated with disease severity and autoantibodies and could potentially predict response to newer therapies ...
Ruth Fernandez-Ruiz, Timothy B. Niewold
openaire   +2 more sources

Type I Interferons

International Reviews of Immunology, 1998
Type I interferons (IFNs) constitute a family of structurally related proteins that are all derived from the same ancestral gene and act on a common cell-surface receptor. Contrary to many other cytokines, the production of type I IFNs is not a specialized function, and all cells in the organism can produce them, usually as a result of induction by ...
E, De Maeyer, J, De Maeyer-Guignard
openaire   +2 more sources