Results 231 to 240 of about 153,995 (247)

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

Nature Immunology, 2014
Type I interferon responses are considered the primary means by which viral infections are controlled in mammals. Despite this view, several pathogens activate antiviral responses in the absence of type I interferons.
Charlotte Odendall, Fabrizia Stavru, Hélène Bierne   +2 more
exaly   +2 more sources

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RELA tunes innate-like interferon I/III responses in human T cells

Journal of Experimental Medicine, 2023
Nadia Jeremiah, Hermine FERRÁN, Konstantina Antoniadou   +2 more
exaly  

Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial

Lancet, The, 2008
Alexander Mm Eggermont, Mario Santinami, Alessandro Testori   +2 more
exaly  

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

Cell Reports, 2020
Patrick J Metz, Keith A Ching, Tao Xie
exaly  

Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

Lancet, The, 2007
Alain Ravaud, Sérgio Bracarda, Cezary Szczylik   +2 more
exaly  

Molecular Mechanisms of Antifibrotic Effect of Interferon Gamma in Bleomycin-Mouse Model of Lung Fibrosis: Downregulation of TGF-β and Procollagen I and III Gene Expression

Experimental Lung Research, 1995
G Gurujeyalakshmi, Shri N Giri
exaly  

RECOMBINANT HUMAN INTERFERON ALFA-A SUPPRESSES HTLV-III REPLICATION IN VITRO

Lancet, The, 1985
T R Rota, R T Schooley, J C Kaplan
exaly  

Role of autophagy in inhibiting the proliferation of A549 cells by type III interferon

Cell Biology International, 2019
Dongmei Gao, Xiaoqin Yu, Yong Fang
exaly