Exploration of chlamydial type III secretion system reconstitution in Escherichia coli. [PDF]
PLoS ONE, 2012 BACKGROUND:Type III secretion system is a virulent factor for many pathogens, and is thought to play multiple roles in the development cycle and pathogenesis of chlamydia, an important human pathogen.
Xiaofeng Bao +2 more
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Yersinia type III secretion : send in the effectors [PDF]
The Journal of cell biology, 2002 Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block ...
Cornelis, G. R.
core +8 more sources
Type III Secretion Effectors with Arginine N-Glycosyltransferase Activity [PDF]
Microorganisms, 2020 Type III secretion systems are used by many Gram-negative bacterial pathogens to inject proteins, known as effectors, into the cytosol of host cells. These virulence factors interfere with a diverse array of host signal transduction pathways and cellular
Juan Luis Araujo-Garrido +2 more
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Expression and Quorum Sensing Regulation of Type III Secretion System Genes of Vibrio harveyi during Infection of Gnotobiotic Brine Shrimp. [PDF]
PLoS ONE, 2015 Type III secretion systems enable pathogens to inject their virulence factors directly into the cytoplasm of the host cells. The type III secretion system of Vibrio harveyi, a major pathogen of aquatic organisms and a model species in quorum sensing ...
H A Darshanee Ruwandeepika +3 more
doaj +4 more sources
Natural Product Type III Secretion System Inhibitors [PDF]
Antibiotics, 2019 Many known inhibitors of the bacterial type III secretion system (T3SS), a virulence factor used by pathogenic bacteria to infect host cells, are natural products.
Heather A. Pendergrass, Aaron E. May
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Type III secretion proteins PcrV and PcrG from
BMC Microbiology, 2003 Background Pseudomonas aeruginosa, an increasingly prevalent opportunistic pathogen, utilizes a type III secretion system for injection of toxins into host cells in order to initiate infection.
Chabert Jacqueline +7 more
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Curcumin inhibits type III secretion of Pseudomonas aeruginosa [PDF]
PeerJPseudomonas aeruginosa is a remarkable opportunistic bacterium that represents a global health concern, due to its ubiquity and high levels of antibiotic resistance.
Miguel Diaz-Guerrero +7 more
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<i>Salmonella</i> Type III Secretion System Effectors. [PDF]
Int J Mol SciSalmonella is estimated to infect between 200 million and over 1 billion people per year. The exact number is not known, as many cases go unreported. Integral to the pathogenesis of Salmonella, as well as numerous other Gram-negative pathogens, is its type III effectors.
Worley MJ.
europepmc +3 more sources
The FliI ATPase couples ATP hydrolysis to substrate switching in bacterial flagellar type-III secretion [PDF]
mBioBacterial flagella are assembled by a specialized type-III secretion system that exports structural subunits in a defined order. While the ATPase FliI is known to couple ATP hydrolysis to substrate translocation, its role in the transition between early ...
Rosa Einenkel +5 more
doaj +2 more sources
Type III secretion in Yersinia: injectisome or not? [PDF]
PLoS Pathogens, 2012 Under certain conditions, pathogens like Yersinia secrete high levels of proteins. This ability correlates with cytotoxicity and virulence. The complete inactivity of the secreted proteins when added directly to host cells stimulated research to disclose this “non-AB toxin mechanism” of virulence, and eventually led to the discovery of the type III ...
Tomas Edgren +3 more
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