Results 111 to 120 of about 24,060,770 (296)

Phage tail-like particles are versatile bacterial nanomachines – A mini-review

Journal of Advanced Research, 2019
Type VI secretion systems and tailocins, two bacterial phage tail-like particles, have been reported to foster interbacterial competition. Both nanostructures enable their producer to kill other bacteria competing for the same ecological niche ...
Sascha Patz, Yvonne Becker, Katja R. Richert-Pöggeler, Beatrice Berger, Silke Ruppel, Daniel H. Huson, Matthias Becker   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

DotU expression is highly induced during in vivo infection and responsible for virulence and Hcp1 secretion in avian pathogenic Escherichia coli

Frontiers in Microbiology, 2014
Type VI secretion systems (T6SSs) contribute to pathogenicity in many pathogenic bacteria. Three distinguishable T6SS loci have been discovered in avian pathogenic Escherichia coli (APEC).
Shaohui eWang, Jianjun eDai, Qingmei eMeng, Qingmei eMeng, Xiangan eHan, Yue eHan, Yichao eZhao, Denghui eYang, Chan eDing, Shengqing eYu   +9 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Adhesion and host cell modulation: critical pathogenicity determinants of Bartonella henselae [PDF]

, 2011
Bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type IV secretion systems.
Kempf Volkhard AJ, Volkhard AJ Kempf, Kempf, Volkhard A. J., Bettina Franz, Franz, Bettina, Franz Bettina   +5 more
core   +1 more source

Type VI secretion system regulation as a consequence of evolutionary pressure

Journal of Medical Microbiology, 2013
The type VI secretion system (T6SS) is a mechanism evolved by Gram-negative bacteria to negotiate interactions with eukaryotic and prokaryotic competitors. T6SSs are encoded by a diverse array of bacteria and include plant, animal, human and fish pathogens, as well as environmental isolates.
Sarah T, Miyata, Verena, Bachmann, Stefan, Pukatzki   +2 more
openaire   +2 more sources

Identification and functional characterization of a fructose-inducible phosphotransferase system in Azospirillum brasilense Sp7

Applied and Environmental Microbiology
Plant growth-promoting rhizobacterium Azospirillum brasilense Sp7 utilizes fructose efficiently via a fructose phosphotransferase system (Fru-PTS). Its genome encodes two putative Fru-PTS, each consisting of FruB (EIIA), FruK (Pfk), and FruA (EIIBC ...
Sushant Rai, Vijay Shankar Singh, Parikshit Gupta, Anil Kumar Tripathi   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen burkholderia pseudomallei K96243 [PDF]

, 2010
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease ...
Wilkinson Paul A., Dowling, Andrea J., Matthew T G Holden, Richard W. Titball, Nicholas R. Waterfield, Paul A Wilkinson, Titball, Richard W., Quail, MA, Bentley Stephen D., Holden Matthew T. G., Richard W Titball, Bentley, SD, Julia Reger, Quail, Michael A., Waterfield Nicholas R., Stephen D. Bentley, Waterfield, NR, Andrea J Dowling, Stephen D Bentley, Wilkinson, Paul A., Bentley, Stephen D., Holden, Matthew T. G., ffrench-Constant, Richard H., ffrench-Constant Richard H., ffrench-Constant, Richard, Richard H. ffrench-Constant, Paul A. Wilkinson, Matthew T. G. Holden, Michael A. Quail, Michael A Quail, Waterfield, Nicholas R., Dowling Andrea J., Reger, J, Titball Richard W., Nicholas R Waterfield, Reger, Julia, Quail Michael A., Andrea J. Dowling, Andrea J. Dowling, Richard H Ffrench-Constant, Dowling, AJ, Holden, Matthew, Wilkinson, PA, Reger Julia   +43 more
core   +1 more source

The Type VI secretion system: a versatile bacterial weapon

Microbiology, 2019
The Type VI secretion system (T6SS) is a protein nanomachine that is widespread in Gram-negative bacteria and is used to translocate effector proteins directly into neighbouring cells. It represents a versatile bacterial weapon that can deliver effectors into distinct classes of target cells, playing key roles in inter-bacterial competition and ...
openaire   +3 more sources