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The Francisella Type VI Secretion System [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia.
Daniel L. Clemens   +2 more
doaj   +6 more sources

Type VI secretion system : secretion by a contractile nanomachine [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek, Basler M
core   +6 more sources

Structure and Activity of the Type VI Secretion System [PDF]

open access: yesMicrobiology Spectrum, 2019
International audienceThe type VI secretion system (T6SS) is a multiprotein machine that uses a spring-like mechanism to inject effectors into target cells.
Durand, Eric   +5 more
core   +4 more sources

Adaptor proteins of type VI secretion system effectors [PDF]

open access: yesTrends in Microbiology, 2017
Bacteria use the type VI secretion system (T6SS) to kill neighboring cells. One key feature of the T6SS is the secretion of diverse effectors. Here, we discuss six publications that describe three superfamilies of T6SS proteins, each dedicated to mediate
Unterweger, D, Kostiuk, B, Pukatzki, S
core   +4 more sources

Tagging the type VI secretion system [PDF]

open access: yesNature Microbiology, 2018
International audienceBacteria use multiple mechanisms to secrete proteins across their envelope and gain access to resources in their niche. The type VI secretion system (T6SS) specializes in injecting toxic protein effectors by direct contact, killing ...
Francetic, Olivera
core   +3 more sources

The type VI secretion system: a tubular story [PDF]

open access: yesThe EMBO Journal, 2009
The molecular mechanism by which proteins are secreted in gram-negative bacteria is supported by nanomachines called type I to type VI secretion systems (T1SS to T6SS).
Filloux, Alain, Alain Filloux
core   +5 more sources

Presence and absence of type VI secretion systems in bacteria [PDF]

open access: yesMicrobiology (Reading, England), 2022
The type VI secretion system (T6SS) is a molecular puncturing device that enables Gram-negative bacteria to kill competitors, manipulate host cells and take up nutrients. Who would want to miss such superpowers?
Unterweger, D. ; https://orcid.org/   +8 more
core   +5 more sources

Roles of Type VI Secretion System in Transport of Metal Ions [PDF]

open access: yesFrontiers in Microbiology, 2021
The type VI secretion system (T6SS) is a transmembrane protein nanomachine employed by many gram-negative bacteria to directly translocate effectors into adjacent cells or the extracellular milieu, showing multiple functions in both interbacterial ...
Xiaobing Yang   +4 more
doaj   +3 more sources

A binary effector module secreted by a type VI secretion system [PDF]

open access: yesThe EMBO Reports, 2021
ABSTRACT Gram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Cargo effectors are secreted by binding non-covalently to the T6SS apparatus. Occasionally, effector secretion is assisted by an adaptor protein, although the adaptor itself is not secreted.
Dar, Yasmin   +3 more
openaire   +3 more sources

Type VI secretion system [PDF]

open access: yesCurrent Biology, 2015
Bacteria employ a variety of tools to survive in a competitive environment. Salomon and Orth describe one such tool-the Type 6 Secretion Systems used by bacteria to deliver a variety of toxins into competing cells.
Salomon, Dor, Orth, Kim
openaire   +2 more sources

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