Acinetobacter type VI secretion system comprises a non-canonical membrane complex.
A. baumannii can rapidly acquire new resistance mechanisms and persist on abiotic surface, enabling the colonization of asymptomatic human host. In Acinetobacter the type VI secretion system (T6SS) is involved in twitching, surface motility and is used ...
Ona Kandolo +11 more
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CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Haas, Rainer +17 more
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Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James +16 more
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VgrG2 of type VI secretion system 2 of Vibrio parahaemolyticus induces autophagy in macrophages
Type VI secretion system (T6SS) is a macromolecular transenvelope machine encoded within the genomes of several proteobacteria species. Vibrio parahaemolyticus contains two putative T6SS systems, VpT6SS1 and VpT6SS2, both contributing to adherence to ...
Ying eYu +5 more
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Toxins, mutations and adaptations
The toxins that some bacteria secrete to kill off rival species can also generate mutations that help toxin-resistant populations adapt to new environments.
Maarten De Jong, Neal M Alto
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Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. [PDF]
BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis where the highest reported incidence world wide is in the Northeast of Thailand, where saline soil and water are prevalent.
Stabler, Richard A. +30 more
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The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Martina Lazzaro +2 more
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Calcium Promotes T6SS-Mediated Killing and Aggregation between Competing Symbionts
Bacteria use a variety of strategies to exclude competitors from accessing resources, including space within a host niche. Because these mechanisms are typically costly to deploy, they are often tightly regulated for use in environments where the ...
Lauren Speare +2 more
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Type VI Secretion System Helps Find a Niche [PDF]
Type VI secretion systems (T6SSs) deliver toxins into target cells and thus play a role in bacterial warfare. In this issue of Cell Host & Microbe, Ma et al. (2014) demonstrate that T6SS-dependent attack during interbacterial competition in the host context enables niche colonization by Agrobacterium tumefaciens.
Kapitein, Nicole, Mogk, Axel
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Functional diversity of accessory factors of the type VI secretion system
The type VI secretion system (T6SS) is a nanomachine utilized by Gram-negative bacteria to secrete toxic effectors. The T6SS is employed against both prokaryotic and eukaryotic targets, allowing for competitive advantage and virulence of the attackers in
Casey Latario, Benjamin D. Ross
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