Results 51 to 60 of about 25,500,999 (291)

Toxins, mutations and adaptations

open access: yeseLife, 2021
The toxins that some bacteria secrete to kill off rival species can also generate mutations that help toxin-resistant populations adapt to new environments.
Maarten De Jong, Neal M Alto
doaj   +1 more source

Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. [PDF]

open access: yes, 2010
BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis where the highest reported incidence world wide is in the Northeast of Thailand, where saline soil and water are prevalent.
Stabler, Richard A.   +30 more
core   +1 more source

A View to a Kill: The Bacterial Type VI Secretion System [PDF]

open access: yesCell Host & Microbe, 2014
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and mechanistically analogous to an intracellular membrane-attached contractile phage tail. Recent studies determined that a rapid conformational change in the structure of a sheath protein complex propels T6SS spike and tube components along with antibacterial and ...
Ho, Brian T.   +2 more
openaire   +2 more sources

Molecular weaponry:diverse effectors delivered by the Type VI secretion system [PDF]

open access: yes, 2015
The Type VI secretion system is a widespread bacterial nanomachine, used to deliver toxins directly into eukaryotic or prokaryotic target cells. These secreted toxins, or effectors, act on diverse cellular targets, and their action provides the attacking
Coulthurst, Sarah J.; id_orcid   +2 more
core   +1 more source

The Type VI Secretion System: A Dynamic System for Bacterial Communication?

open access: yesFrontiers in Microbiology, 2017
Numerous studies in Gram-negative bacteria have focused on the Type VISecretion Systems (T6SSs), Quorum Sensing (QS), and social behavior, such as in biofilms.
Mathias Gallique   +2 more
doaj   +1 more source

Calcium Promotes T6SS-Mediated Killing and Aggregation between Competing Symbionts

open access: yesMicrobiology Spectrum, 2022
Bacteria use a variety of strategies to exclude competitors from accessing resources, including space within a host niche. Because these mechanisms are typically costly to deploy, they are often tightly regulated for use in environments where the ...
Lauren Speare   +2 more
doaj   +1 more source

The tip of the VgrG spike is essential to functional type VI secretion system assembly in Acinetobacter baumannii [PDF]

open access: yes, 2020
The type VI secretion system (T6SS) is a critical weapon in bacterial warfare between Gram-negative bacteria. Although invaluable for niche establishment, this machine represents an energetic burden to its host ...
Feldman, Mario F   +5 more
core   +1 more source

T6SS: A Key to Pseudomonas’s Success in Biocontrol?

open access: yesMicroorganisms, 2023
Bacteria from the genus Pseudomonas have been extensively studied for their capacity to act as biological control agents of disease and pests and for their ability to enhance and promote crop production in agricultural systems.
Edwin D. Navarro-Monserrat   +1 more
doaj   +1 more source

Type VI Secretion System: A Modular Toolkit for Bacterial Dominance [PDF]

open access: yesFuture Microbiology, 2019
Bacteria use toxin delivery systems, such as the type VI secretion system (T6SS), to antagonize competitors. The T6SS transports toxins, called effectors, directly into recipient cells. In the absence of cognate immunity proteins that protect against kin-intoxication, these effectors target conserved and essential cell components resulting in growth ...
Jana, Biswanath, Salomon, Dor
openaire   +2 more sources

Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

open access: yesFrontiers in Microbiology, 2018
Pseudomonas aeruginosa can manipulate eukaryotic host cells using secreted effectors delivered by the type III or the type VI Secretion Systems (T3SS and T6SS). The T3SS allows the injection of bacterial effectors (Exo toxins) into eukaryotic cell.
Thibaud Boulant   +10 more
doaj   +1 more source

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