Results 31 to 40 of about 25,500,999 (291)
Established microbial colonies can survive type VI secretion assault [PDF]
, 2015 Type VI secretion (T6S) is a cell-to-cell injection system that can be used as a microbial weapon. T6S kills vulnerable cells, and is present in close to 25% of sequenced Gram-negative bacteria.
Ned S Wingreen +16 more
core +2 more sources
Structure of the Type VI Secretion System Contractile Sheath [PDF]
Cell, 2015 Bacteria use rapid contraction of a long sheath of the type VI secretion system (T6SS) to deliver effectors into a target cell. Here, we present an atomic-resolution structure of a native contracted Vibrio cholerae sheath determined by cryo-electron microscopy. The sheath subunits, composed of tightly interacting proteins VipA and VipB, assemble into a
Kudryashev, Mikhail +9 more
openaire +7 more sources
Type VI secretion: a beginner's guide [PDF]
, 2008 Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Bailey, Christopher +7 more
core +1 more source
The rise of the Type VI secretion system [PDF]
F1000Prime Reports, 2013 Bacterial cells have developed multiple strategies to communicate with their surrounding environment. The intracellular compartment is separated from the milieu by a relatively impermeable cell envelope through which small molecules can passively diffuse, while larger macromolecules, such as proteins, can be actively transported.
openaire +3 more sources
Type VI secretion systems in plant‐associated bacteria [PDF]
Environmental Microbiology, 2017 Summary The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into prokaryotic or eukaryotic cells and is thus involved in both host manipulation and interbacterial competition. The T6SS is widespread among Gram‐negative bacteria, mostly within the Proteobacterium Phylum.
Patricia Bernal +2 more
openaire +4 more sources
Trade-offs constrain adaptive pathways to type VI secretion system survival
iScience, 2023 Summary: The Type VI Secretion System (T6SS) is a nano-harpoon used by many bacteria to inject toxins into neighboring cells. While much is understood about mechanisms of T6SS-mediated toxicity, less is known about the ways that competitors can defend ...
Kathryn A. MacGillivray +7 more
doaj +1 more source
Diversity of the type VI secretion systems in the Neisseria spp
Microbial Genomics, 2023 Complete Type VI Secretion Systems were identified in the genome sequence data of Neisseria subflava isolates sourced from throat swabs of human volunteers.
Alan Calder, Lori A.S. Snyder
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A novel stabilization mechanism for the type VI secretion system sheath [PDF]
Proceedings of the National Academy of Sciences, 2021 Significance The T6SS is a microscopic harpoon that bacteria use to deliver toxins into neighboring cells. While its complex assembly process has been extensively studied, it remains unclear how the two forms (long and short) of the pivotal TssA protein affect T6SS function.
Bernal, Patricia +6 more
openaire +4 more sources
Frontiers in Microbiology, 2019 Virulent Aeromonas hydrophila causes severe motile Aeromonas septicemia in warmwater fishes. In recent years, channel catfish farming in the U.S.A. and carp farming in China have been affected by virulent A.
Hasan C. Tekedar +5 more
doaj +1 more source
Architecture and assembly of the Type VI secretion system
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014 The Type VI secretion system (T6SS) delivers protein effectors to diverse cell types including prokaryotic and eukaryotic cells, therefore it participates in inter-bacterial competition and pathogenesis. The T6SS is constituted of an envelope-spanning complex anchoring a cytoplasmic tubular edifice.
Zoued, Abdelrahim +8 more
openaire +4 more sources