Results 21 to 30 of about 25,500,999 (291)
Secretin interactions in the type II secretion system [PDF]
, 2012 PhDThe type II secretion system (T2SS) is the major terminal branch of the general secretory pathway. It is composed of 12-15 proteins, most in multiple copies, and spans the inner and outer membranes of Gram-negative bacteria.
Gu, Shuang
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The Versatile Type VI Secretion System [PDF]
Microbiology Spectrum, 2016 ABSTRACT Bacterial type VI secretion systems (T6SSs) function as contractile nanomachines to puncture target cells and deliver lethal effectors. In the 10 years since the discovery of the T6SS, much has been learned about the structure and function of this versatile protein secretion apparatus.
Christopher J, Alteri, Harry L T, Mobley
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Distribution and diversity of bacterial secretion systems across metagenomic datasets [PDF]
, 2012 Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from ...
Egan, Frank +3 more
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Marker for type VI secretion system effectors [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance The recently discovered type VI secretion system (T6SS) is used by Gram-negative bacteria to deliver effector proteins into both eukaryotic and prokaryotic neighboring cells to mediate virulence and competition, respectively.
Dor, Salomon +7 more
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Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins. [PDF]
The Journal of biological chemistry, 2011 Pseudomonas aeruginosa is a Gram-negative bacterium causing chronic infections in cystic fibrosis patients. Such infections are associated with an active type VI secretion system (T6SS), which consists of about 15 conserved components, including the AAA+ ATPase, ClpV. The T6SS secretes two categories of proteins, VgrG and Hcp.
Hachani, Abderrahman +6 more
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, 2023 The original dates and figures in Effectors of the type VI secretion system have the potential to be modified into antimicrobial ...
lu, W (via Mendeley Data), lu, wenjia
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A DNase Type VI Secretion System Effector Requires Its MIX Domain for Secretion
Microbiology Spectrum, 2022 Gram-negative bacteria often employ the type VI secretion system (T6SS) to deliver diverse cocktails of antibacterial effectors into rival bacteria.
Chaya Mushka Fridman +4 more
doaj +1 more source
Structural biology of type VI secretion systems [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2012 Type VI secretion systems (T6SSs) are transenvelope complexes specialized in the transport of proteins or domains directly into target cells. These systems are versatile as they can target either eukaryotic host cells and therefore modulate the bacteria–host interaction and pathogenesis or bacterial cells and therefore facilitate access to a specific ...
Cascales, E., Cambillau, Christian
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Type VI Secretion Systems and the Gut Microbiota [PDF]
Microbiology Spectrum, 2019 ABSTRACT The human colonic microbiota is a dense ecosystem comprised of numerous microbes, including bacteria, phage, fungi, archaea, and protozoa, that compete for nutrients and space. Studies are beginning to reveal the antagonistic mechanisms that gut bacteria use to compete with other members of this ecosystem.
Michael J, Coyne, Laurie E, Comstock
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Structure and Regulation of the Type VI Secretion System [PDF]
Annual Review of Microbiology, 2012 The type VI secretion system (T6SS) is a complex and widespread gram-negative bacterial export pathway with the capacity to translocate protein effectors into a diversity of target cell types. Current structural models of the T6SS indicate that the apparatus is composed of at least two complexes, a dynamic bacteriophage-like structure and a cell ...
Silverman, Julie +3 more
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