Results 61 to 70 of about 24,060,770 (296)
Integrating signals to drive type VI secretion system killing [PDF]
Ministerio de Ciencia, Innovación y Universidades RTI2018-096936-J ...
Patricia Bernal +2 more
openaire +4 more sources
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Characterization of the SPI-1 and Rsp type three secretion systems in Pseudomonas fluorescens F113 [PDF]
Pseudomonas fluorescens F113 is a plant growthpromoting rhizobacterium (PGPR) isolated from the sugar beet rhizosphere. The recent annotation of the F113 genome sequence has revealed that this strain encodes a wide array of secretion systems, including ...
Matthieu Barret +12 more
core +1 more source
Crosstalk Between Type VI Secretion System and Mobile Genetic Elements
Many bacterial processes require cell-cell contacts. Such are the cases of bacterial conjugation, one of the main horizontal gene transfer mechanisms that physically spreads DNA, and the type VI secretion systems (T6SSs), which deploy antibacterial ...
Arancha Peñil-Celis +1 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The evolution of the type VI secretion system as a disintegration weapon
The type VI secretion system (T6SS) is a nanomachine used by many bacteria to drive a toxin-laden needle into other bacterial cells. Although the potential to influence bacterial competition is clear, the fitness impacts of wielding a T6SS are not well understood.
Smith, WPJ +6 more
openaire +6 more sources
Insights into Klebsiella pneumoniae type VI secretion system transcriptional regulation
Background Klebsiella pneumoniae (KP) is an opportunistic pathogen that mainly causes respiratory and urinary tract infections. The frequent occurrence of simultaneously virulent and multiple drug-resistant isolates led WHO to include this species in the
Victor Augusto Araújo Barbosa +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Assessing toxicity and competitive fitness of Vibrio isolates from coastal waters in Israel
Several species of aquatic bacteria belonging to the genus Vibrio are emerging pathogens of humans and marine animals. Vibrio-associated infections have been shown to correlate with the increase in the oceans’ surface water temperatures.
Katarzyna Kanarek +5 more
doaj +1 more source
Roles of Type VI Secretion System in Transport of Metal Ions
The type VI secretion system (T6SS) is a transmembrane protein nanomachine employed by many gram-negative bacteria to directly translocate effectors into adjacent cells or the extracellular milieu, showing multiple functions in both interbacterial ...
Xiaobing Yang +4 more
doaj +1 more source

