Results 121 to 130 of about 63,697 (228)

A Simple Method for RNA‐Seq of Manually Isolated Chromatophores in Oryzias Fishes

Development, Growth &Differentiation, Volume 68, Issue 3, April 2026.
ABSTRACT RNA sequencing (RNA‐seq) has become an essential tool for analyzing gene expression and exploring cell type–specific transcriptomes. However, sample preparation and quality control remain challenging, as current approaches typically rely on dissecting tissues containing mixed cell populations or using flow cytometry to isolate fluorescently ...
Makoto Goda, Asuka Miyagi, Keisuke Sugiwaka, Masakatsu Watanabe, Manabu Bessho‐Uehara, Masahiko Hibi, Atsushi Toyoda, Rieko Tanaka, Kawilarang W. A. Masengi, Kazunori Yamahira, Satoshi Ansai, Hisashi Hashimoto   +11 more
wiley   +1 more source

A Novel Mouse Model of Sympathoadrenal Catecholamine Deficiency by Ablation of the Tyrosine Hydroxylase Gene With Slc6a4‐Cre

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Tyrosine hydroxylase (TH) is a rate‐limiting enzyme for catecholamine synthesis. In this study, we generated a novel Th gene conditional knockout mouse line by crossing Th‐flox mice with Slc6a4‐Cre mice. To our surprise, TH expression was largely lost in the adrenal medulla and sympathetic neurons in the conditional knockout mice.
Ryohei Ogawa, Ryo Fukumoto, Satoshi Hara, Nobuhiro Hayashi, Hiroshi Ichinose   +4 more
wiley   +1 more source

Transaminase and Norcoclaurine Synthase One‐Pot Cascades Towards (1S)‐Tetrahydroisoquinolines

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
A TAm‐NCS cascade towards THIQs has been established, starting from amines with the in situ production of aldehydes. The cascade was used with a variety of nonfunctionalized and functionalized amines, and reaction conditions modified to enhance formation of the desired cross‐products.
Jianxiong Zhao, Yeke Ni, Yu Wang, John M. Ward, Jack W. E. Jeffries, Helen C. Hailes   +5 more
wiley   +1 more source

NEUROSPORA TYROSINASE

Journal of Biological Chemistry, 1952
N H, HOROWITZ, S C, SHEN
openaire   +2 more sources

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Anti-Melanogenic Effects of Cnidium monnieri Extract via p38 Signaling-Mediated Proteasomal Degradation of Tyrosinase

Plants
Cnidium monnieri fructus is widely used in traditional Oriental medicine for treating female genital disorders, male impotence, frigidity, and skin-related conditions in East Asia. However, the role of C.
Soon Ho Choi, Hyunggun Kim, Jeon Hwang-Bo, Kyoung Mi Kim, Jeong Eun Kwon, Sung Ryul Lee, Sun Ha Hwang, Se Chan Kang, Yeong-Geun Lee   +8 more
doaj   +1 more source

Expression of Functional Recombinant Mussel Adhesive Protein Mgfp-5 in Escherichia coli [PDF]

Mussel adhesive proteins have been suggested as a basis for environmentally friendly adhesives for use in aqueous conditions and in medicine. However, attempts to produce functional and economical recombinant mussel adhesive proteins (mainly foot protein
CHA, HYUNG JOON, Hwang, DS, Jong Hyub Jun, MOON, WON KYU, Yoo Hyo Jin   +4 more
core   +1 more source

In Silico Identification and Molecular Mechanism of Novel Tyrosinase Inhibitory Peptides Derived from Nacre of Pinctada martensii

Marine Drugs
Pearl and nacre powders have been valuable traditional Chinese medicines with whitening properties for thousands of years. We utilized a high-temperature and high-pressure method along with compound enzyme digestion to prepare the enzymatic hydrolysates ...
Fei Li, Haisheng Lin, Xiaoming Qin, Jialong Gao, Zhongqin Chen, Wenhong Cao, Huina Zheng, Shaohe Xie   +7 more
doaj   +1 more source

Enhancement Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression of Macrobrachium Rosenbergii Fed with Aqueous Morinda Citrifolia Leaves Extract-Supplemented Diet [PDF]

, 2018
Morinda citrifolia, known commercially as noni is often used for enhance immunity, these plant rich of phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed with diets containing of aqueous M.
Chang, C. C. (Chin), Halim, A. M. (Atika), Prajitno, A. (Arief)   +2 more
core  

Discovery of bis-thiourea derivatives as potent tyrosinase inhibitors: combined experimental and computational study

Journal of Enzyme Inhibition and Medicinal Chemistry
Tyrosinase, a key enzyme in melanin synthesis, serves as a primary target for developing depigmenting agents. The search for novel tyrosinase inhibitors is needed due to the adverse effects of current inhibitors.
Sahachai Sabuakham, Sutita Nasoontorn, Napat Nuramrum, Atit Silsirivanit, Thanyada Rungrotmongkol, Ratchanok Pingaew, Panupong Mahalapbutr   +6 more
doaj   +1 more source