Results 21 to 30 of about 12,040 (235)
A tyrosinase inhibitor from Aspergillus niger [PDF]
Journal of Food Science and Technology, 2014 Tyrosinase, in the presence of oxygen, is the main culprit in post harvest browning of food products, resulting in the drop in its commercial value. In an effort to seek natural tyrosinase inhibitors for food applications, a screening programme was undertaken. Of the 26 fungal cultures isolated from soil samples of Agumbe forest, India, one isolate S16,
K Y, Vasantha +2 more
openaire +3 more sources
A comprehensive review on tyrosinase inhibitors [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose,
Samaneh Zolghadri +6 more
openaire +3 more sources
Computational and Structural Biotechnology Journal, 2019 Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover potent tyrosinase inhibitors, we systematically designed and synthesized ...
Hee Jin Jung +6 more
doaj +1 more source
Benzylidene-6-hydroxy-3,4-dihydronaphthalenone chalconoids as potent tyrosinase inhibitors
Research in Pharmaceutical Sciences, 2021 Background and purpose: Tyrosinase enzyme has a key role in melanin biosynthesis by converting tyrosine into dopaquinone. It also participates in the enzymatic browning of vegetables by polyphenol oxidation. Therefore, tyrosinase inhibitors are useful in
Sara Ranjbar +5 more
doaj +1 more source
Antityrosinase activity of Euphorbia characias extracts [PDF]
PeerJ, 2015 Tyrosinase is a well-known key enzyme in melanin biosynthesis and its inhibitors have become increasingly important because of their potential use as hypopigmenting agents.
Francesca Pintus +3 more
doaj +2 more sources
Molecules, 2017 Tyrosinase is the rate-limiting enzyme critical for melanin synthesis. It controls pigmentation in the skin. Activation of tyrosinase is currently the most common approach in the development of tanning and haircare products.
You Chul Chung +6 more
doaj +1 more source
A Competitive Inhibitor of Tyrosinase [PDF]
Australian Journal of Biological Sciences, 1951 The kinetics of the activation of catechol by tyrosinase prepared from the potato and the mushroom, and of its inhibition by sodium m-hydroxybenzoate, have been studied. The enzyme-substrate dissociation constants differed markedly between the two enzyme sources (K.
openaire +2 more sources
Molecules, 2022 This research work focuses on the potential application of an organic compound, santalol, obtained from santalum album, in the inhibition of the enzyme tyrosinase, which is actively involved in the biosynthesis of melanin pigment.
Nabeel Ali +13 more
doaj +1 more source
An Updated Review of Tyrosinase Inhibitors [PDF]
International Journal of Molecular Sciences, 2009 Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing. Neither hyperpigmentation in human skin nor enzymatic browning in fruits are desirable.
openaire +2 more sources
Phlorotannins Derived From the Brown Alga as Tyrosinase Inhibitors
Natural Product Communications, 2021 Tyrosinase catalyzes hydroxylation of L-tyrosine and dehydrogenation of L-DOPA in the melanin biosynthesis pathway. Tyrosinase inhibitors have potential use as cosmetic whitening agents and for preventing seafood deterioration. In this report, tyrosinase
Hideyuki Kurihara, Kazuki Kujira
doaj +1 more source