Results 31 to 40 of about 568,389 (237)

Tyrosinase inhibitors and insecticidal materials produced by Burkholderia cepacia using squid pen as the sole carbon and nitrogen source [PDF]

, 2014
Reports of tyrosinase inhibitors from microorganisms are rare. A tyrosinase inhibitor- and insecticidal materials-producing bacterium, strain TKU026, was isolated from Taiwanese soil and identified as Burkholderia cepacia. Among the tested chitin-
Hsua, Chia-Hao; Nguyenb, Anh Dzung; Chen, Yung-Wei; Wang, San-Lang, Wang, San-Lang   +1 more
core   +1 more source

Rational design of an N-terminal cysteine-containing tetrapeptide that inhibits tyrosinase and evaluation of its mechanism of action

Current Research in Food Science, 2023
There has been a resurgence of interest in bioactive peptides as therapeutic agents. This is particularly interesting for tyrosinase, which can be inhibited by thiol-containing peptides.
Anupong Joompang, Preeyanan Anwised, Sompong Klaynongsruang, Lapatrada Taemaitree, Anuwat Wanthong, Kiattawee Choowongkomon, Sakda Daduang, Somporn Katekaew, Nisachon Jangpromma   +8 more
doaj   +1 more source

Novel tyrosinase inhibitory peptide with free radical scavenging ability

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Tyrosinase is a key enzyme involved in melanin synthesis. Therefore, various tyrosinase inhibitors have been screened by researchers in recent years. In the present study, we discovered a novel tyrosinase inhibitor, a peptide ECGYF (named EF-5), with ...
Zhiwei Shen, Yujiao Wang, Zhen Guo, Tingyuan Tan, Yi Zhang   +4 more
doaj   +1 more source

Kinetics Investigation on Mushroom Tyrosinase Inhibition of Proso Millet

Journal of Chemistry, 2018
Proso millet (Panicum miliaceum) is rich in nutritive components and is widely used as a human food, feed and forage for animals, and fuel. This study investigated the effect of a proso millet extract on the inhibition of tyrosinase, a key enzyme in ...
Wen-Ying Huang, Hui-Ju Chen, Chia-Ching Lin, Chin-Shuh Chen, Yung-Sheng Lin   +4 more
doaj   +1 more source

An Updated Review of Tyrosinase Inhibitors [PDF]

International Journal of Molecular Sciences, 2009
Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing. Neither hyperpigmentation in human skin nor enzymatic browning in fruits are desirable.
openaire   +2 more sources

Experimental Evidence and Mechanistic Description of the Phenolic H‑Transfer to the Cu₂O₂ Active Site of oxy-Tyrosinase

, 2023
Tyrosinase is a ubiquitous coupled binuclear copper enzyme that activates O2 toward the regioselective monooxygenation of monophenols to catechols via a mechanism that remains only partially defined.
Martin Srnec (1263150), Agnieszka Stańczak (17175044), Jake W. Ginsbach (1645351), Ioannis Kipouros (17175041), Lubomír Rulíšek (1263147), Eleanor M. Dunietz (17175047), Edward I. Solomon (177653)   +6 more
core   +2 more sources

Tyrosinase inhibitors as melanoma sensitizers: Boosting therapeutic efficacy

Supramolecular Materials
Melanoma therapy faces critical challenges due to melanin-mediated resistance mechanisms. The use of tyrosinase inhibitors to suppress tyrosinase activity and reduce melanogenesis, thereby sensitizing melanoma cells, represents a highly promising ...
Yongsheng Li, Kan Yang, Luyang Zhao
doaj   +1 more source

THE ACTIVITY OF GEL EXTRACT MAHKOTA DEWA FRUITS [(Phaleria macrocarpa (Scheff.) Boerl] THROUGH TYROSINASE ENZYME INHIBITOR [PDF]

, 2022
Mahkota dewa fruit [(Phaleria macrocarpa (Scheff.) Boerl] contains benzophenone derivatives which have sun protection activity and flavonoid compounds which can act as tyrosinase inhibitors.
Eff, Aprilita Rina Yanti, Noviyanti, Erika, Pertiwi, Ratih Dyah   +2 more
core   +1 more source

Tyrosinase Inhibitory Activity, 3D QSAR, and Molecular Docking Study of 2,5-Disubstituted-1,3,4-Oxadiazoles

Journal of Chemistry, 2013
In continuation with our research program, in search of potent enzyme tyrosinase inhibitor, a series of synthesized 2,5-disubstituted 1,3,4-oxadiazoles have been evaluated for enzyme tyrosinase inhibitory activity.
Ramesh L. Sawant, Prashant D. Lanke, Jyoti B. Wadekar   +2 more
doaj   +1 more source

Synthesis and Tyrosinase Inhibitory Activity of (E)-5-Benzyl-7- (3-Bromobenzylidene)-3-(3-Bromophenyl)-2-Phenyl-3,3a, 4,5,6,7-Hexahydro-2H-Pyrazolo[4,3-c]Pyridine

Jurnal Kimia Sains dan Aplikasi, 2022
The tyrosinase enzyme plays an essential role in the pigmentation of human skin, fruits, and vegetables. It has been tied with several human skin diseases and post-harvest problems.
Nelly Oscifiani, Noval Herfindo, Rahayu Rahayu, Neni Frimayanti, Adel Zamri   +4 more
doaj   +1 more source