Results 81 to 90 of about 22,420 (243)

Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different flavonoids (1–44) against mushroom tyrosinase was studied, and an
Katarzyna Jakimiuk, Suat Sari, Robert Milewski, Claudiu T. Supuran, Didem Şöhretoğlu, Michał Tomczyk   +5 more
doaj   +1 more source

Poly(neutral red) based hydrogen peroxide biosensor for chromium determination by inhibition measurements [PDF]

, 2014
Amperometric hydrogen peroxide enzyme inhibition biosensors based on horseradish peroxidase (HRP) immobilised on electropolymerised neutral red (NR) or directly on the surface of carbon film electrodes (CFE) have been successfully applied to the ...
Agency for Toxic Substances and Disease Registry (ATSDR), Aisha Attar, Amine, Andrle, Aziz Amine, Bagal-Kestwal, Baral, Barsan, Bozcaarmutlu, Brett, Christopher M.A. Brett, Cornish-Bowden, Costa, Crespilho, Ding, Dixon, Dominguez Renedo, Elci, Evtugyn, Ghica, Ghica, Ghosh, Gouveia-Caridade, Guascito, Han, Ilangovan, Kok, Liu, M. Emilia Ghica, Michel, Michel, Nomngongo, Ouyang, Pauliukaite, Qu, Sezgintürk, Shampao, Sharma, Torres, Tsai, Zeng   +40 more
core   +1 more source

Immunomodulatory Effect of Tilapia (Oreochromis niloticus) Scale Gelatin Peptides in RAW264.7 Macrophages and Caenorhabditis elegans

Food Safety and Health, EarlyView.
ABSTRACT Currently, small‐molecular‐weight collagen peptides are a research hotspot in functional factor development due to their high bioavailability and diverse bioactivities. In this study, gelatin was extracted from tilapia (Oreochromis niloticus) scales by hot water extraction, followed by pepsin hydrolysis and ultrafiltration to obtain the < 3 ...
Ya‐ru Liu, Xu Guo, Shu‐tao Sun, Rui‐rui Zhang, Chao Liu, Ning‐yang Li   +5 more
wiley   +1 more source

Immunological backbone of uveal melanoma: is there a rationale for immunotherapy? [PDF]

, 2019
No standard treatment has been established for metastatic uveal melanoma (mUM). Immunotherapy is commonly used for this disease even though UM has not been included in phase III clinical trials with checkpoint inhibitors.
Alessandra Cassano, Apte, Bill, Blom, Brigida Anna Maiorano, De Vries, Durie, Emilio Bria, Ericsson, Ernesto Rossi, Giampaolo Tortora, Gianluigi Petrone, Giovanni Schinzari, Guido Rindi, Ilaria Grazia Zizzari, Lagouros, Makitie, Maria Antonietta Blasi, Maria Grazia Sammarco, Marianna Nuti, Monica Maria Pagliara, Shaw, Sohn, Vincenzo Fiorentino, Whelchel   +24 more
core   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. [PDF]

, 2014
Coat colours and patterns are highly variable in cats and are determined mainly by several genes with Mendelian inheritance. A 2-bp deletion in agouti signalling protein (ASIP) is associated with melanism in domestic cats. Bengal cats are hybrids between
Davis, BW, Gershony, LC, Helps, CR, Lyons, LA, Murphy, WJ, Penedo, MCT   +5 more
core   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Inhibition effects of Eucalyptus globules Labill. essential oil against tyrosinase

Scientific Reports
Essential oils derived from Eucalyptus globules Labill. (EGEOs) represent a significant class of bioactive metabolites with broad applications in medicinal and pharmaceutical industries. Despite their various biological activities, the potential of EGEOs
Hua Zhu, Xin Zhong
doaj   +1 more source

Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp maritima: from traditional remedies to prospective products [PDF]

, 2018
This work explored the biotechnological potential of the medicinal halophyte Artemisia campestris subsp. maritima (dune wormwood) as a source of health promoting commodities.
A Akrout, A Alam, A Atia, A Buhmann, A Djeridane, A Lopes, AA Jahid, AP Rauter, AS Ribeiro, B Boulanouar, B Saad, CG Pereira, CG Pereira, D Paepe De, DA Viegas, DR Nogueira, F Shahidi, H Akkari, H Riedel, H Sebai, I Dib, I Jallali, JF Sanz, JG Gruenwald, JMJ Vasconcelos, KM Valant-Vetschera, L Barreira, L Custódio, M Karamać, M Saoudi, M Sefi, MJ Rodrigues, MJ Rodrigues, MJ Rodrigues, MP Kähkönen, MTH Khan, N Balasundram, P Pohl, R Ksouri, RW Pero, S Kumar, S Saeidnia, SK Panigrahy, T Oki, T-S Chang, V Sindhi, W Megdiche-Ksouri, YI Kwon, Z Ghlissi   +48 more
core   +2 more sources

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

International Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian, Arnavaz Akhzarmehr, Charise Dallazem Bertol   +2 more
wiley   +1 more source