Results 131 to 140 of about 677,076 (187)
ABSTRACT Introduction Hyperpigmentation disorders impose a substantial clinical and psychosocial burden in individuals with darker skin phototypes, yet remain underrepresented in dermatological research. In India, where a large proportion of the population reports pigmentary concerns, conditions such as post‐inflammatory hyperpigmentation (PIH ...
Mukta Sachdev +10 more
wiley +1 more source
Glucuronyl Glucosyloleanolate: A Safe and Potent AI‐Discovered Depigmenting Saponin
ABSTRACT Purpose Saponins are amphiphilic glycosides found in plants. They have long been used in traditional Asian remedies for their anti‐inflammatory, protective, and rejuvenating properties. One representative, Glucuronyl Glucosyloleanolate (GGO), was recently discovered using a combination of artificial intelligence and experimental testing as a ...
Yannick Quesnel, Michael Gold
wiley +1 more source
The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang +6 more
wiley +1 more source
ABSTRACT S‐Acetyl Glutathione (SAG) is an advanced glutathione derivative designed to improve stability, bioavailability, and efficacy in skin‐lightening applications. Unlike conventional glutathione formulations, SAG offers great cellular uptake and antioxidative properties, making it a promising candidate for managing hyperpigmentation disorders ...
Arie Kusumawardani +4 more
wiley +1 more source
ABSTRACT Background As sunscreens do not completely block ultraviolet radiation, chronic UVR exposure causes cumulative photodamage, increasing premature photoaging, and skin cancer risk. Hence, an optimal sunscreen should incorporate dual benefits, going beyond photoprotection while actively supporting skin barrier recovery post sun‐exposure.
Jiamin Gu +10 more
wiley +1 more source
Strebluses A and B as tyrosinase inhibitors from the stems of <i>Streblus ilicifolius</i> (S. Vidal) Corn. [PDF]
Nguyen HX +10 more
europepmc +1 more source
Microalgae and Macroalgae as Advanced Sources of Tyrosinase Inhibitors. [PDF]
Harasym J, Hałdys K.
europepmc +1 more source
Tyrosinase Inhibitors With Enhanced Potency in Mammalian and Vertebrate Models, N-(2-Mercaptoethyl)benzamide Derivatives: Design, Synthesis, and Evaluation. [PDF]
Ju H +8 more
europepmc +1 more source
New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa. [PDF]
Moon SW +5 more
europepmc +1 more source
Rational design of triazole tyrosinase inhibitors via integrated free energy calculations. [PDF]
Costa NLO +3 more
europepmc +1 more source

