Results 111 to 120 of about 677,076 (187)

A Comprehensive Review on Ferula oopoda (Boiss. and Buhse) Boiss.: Bioactive Compounds and Pharmacological Significance

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ferula oopoda (Boiss. and Buhse) Boiss.: bioactive compounds and pharmacological significance. ABSTRACT Ferula oopoda (Boiss. and Buhse) Boiss. is an ethnomedicinally important species widely used in Central and South Asia for the treatment of gastrointestinal, respiratory, neurological, and parasitic disorders.
Muhammad Ali, Setya Widi Ayuning Permanasari, Shah Iram Niaz, Aizhamal Baiseitova, Abdul Bari Shah, Yuan Bin Cheng   +5 more
wiley   +1 more source

New Primary and Secondary Prevention Measures for Cutaneous Melanoma: A Systematic Review

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Cutaneous melanoma is the deadliest type of skin cancer, with increasing incidence and mortality rates. Therefore, primary and secondary prevention are of utmost importance. Claims The objective is to evaluate new recent evidence on primary and secondary prevention strategies for cutaneous melanoma.
Maria Palau–del–Valle, Elena Bendala–Tufanisco, María Amparo López–Ruiz   +2 more
wiley   +1 more source

Immunomodulatory Effect of Tilapia (Oreochromis niloticus) Scale Gelatin Peptides in RAW264.7 Macrophages and Caenorhabditis elegans

Food Safety and Health, Volume 4, Issue 4, Page 908-922, October 2026.
ABSTRACT Currently, small‐molecular‐weight collagen peptides are a research hotspot in functional factor development due to their high bioavailability and diverse bioactivities. In this study, gelatin was extracted from tilapia (Oreochromis niloticus) scales by hot water extraction, followed by pepsin hydrolysis and ultrafiltration to obtain the < 3 ...
Ya‐ru Liu, Xu Guo, Shu‐tao Sun, Rui‐rui Zhang, Chao Liu, Ning‐yang Li   +5 more
wiley   +1 more source

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio, Simona Scano, Barbara Bellei   +2 more
wiley   +1 more source

Investigations of Some Chlorocresol Hydrazones Against Tyrosinase Enzyme by Molecular Docking Method: In Silico Study

Pharmedicine Journal
Introduction: Tyrosinase, found in various organisms, including plants and mammals, and is responsible for pigmentation as well as the undesirable browning of fruits and vegetables, is a multi-copper enzyme involved in the synthesis of melanin
Necla Kulabas, Fahrettin Bugra Kilic, Sevil Senkardes   +2 more
doaj   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 10, Page 1954-1967, October 2026.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Synthesis and Biological Evaluation of Unsymmetrical Curcumin Analogues as Tyrosinase Inhibitors

, 2013
Synthesis and biological evaluation of unsymmetrical curcumin analogues (UCAs) have been achieved. Tyrosinase inhibitory activities were found for most of the prepared synthetic UCAs. Among them, compounds containing 4-hydroxyl-substituted phenolic rings
Yujing Lu, Yongfu Jiang, Zhiyun Du, Kun Zhang, Xi Zheng, Guihua Xue, Allan H. Conney, Qian Chen, Allan Conney   +8 more
core   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, Volume 6, Issue 10, Page 422-429, October 2026.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Design, synthesis, and evaluation of novel quinazoline-benzo[d]imidazole-indole derivatives as tyrosinase inhibitors

Results in Chemistry
Tyrosinase inhibitors have attracted significant attention for their potential to treat hyperpigmentation disorders and serve as cosmetic agents. This study focuses on the design, synthesis, and evaluation of a novel series of quinazoline-benzo[d ...
Shiva Molaei, Shahrzad Javanshir, Mohammad Mahdavi, Aida Iraji   +3 more
doaj   +1 more source

Rapid and Reversible Inhibition of Tyrosinase Activity by Glucosidase Inhibitors in Human Melanoma Cells

, 1992
The dependence of constitutively expressed tyrosinase (dopa oxidase) activity on glycosylation in lightly pigmented human melanoma cells (MM96E) was determined using tunicamycin (TM), which prevents transfer of oligosaccharide chains to nascent protein ...
Parsons, Peter G, Takahashi, Hiroyuki
core   +1 more source