Results 111 to 120 of about 21,627 (244)

Antimicrobial, antioxidant and anti-tyrosinase properties of extracts of the Mediterranean parasitic plant Cytinus hypocistis [PDF]

open access: yes, 2015
Background: Cytinus is an endophytic parasitic plant occurring in South Africa, Madagascar, and in the Mediterranean region. We have extracted the inflorescences (the only visible part of the plant, emerging from the host roots at the time of blossom) of
Manzo, Giorgia   +5 more
core   +1 more source

Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity

open access: yesSensors, 2019
South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the ...
Ninon G.E.R. Etsassala   +5 more
doaj   +1 more source

JI‐CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7‐H3

open access: yesCancer Science, EarlyView.
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee   +4 more
wiley   +1 more source

Human Tyrosinase Inhibitor in Rum Distillate Wastewater

open access: yesJournal of Oleo Science, 2008
An inhibitor of human tyrosinase activity in rum distillate wastewater was isolated and identified as (S)-(+)-imperanene (1). (S)-(+)-Imperanene significantly inhibited tyrosinase isolated from HMV-II cells (IC(50) 1.85 mM). Inhibition kinetics studies revealed that imperanene is a competitive inhibitor of tyrosinase when L-3,4-dihydroxyphenylalanine ...
Kensaku, Takara   +3 more
openaire   +3 more sources

Investigating Sandoricum koetjape leaf extracts for tyrosinase inhibition: Flavonoid profiles and mechanisms [PDF]

open access: yesE3S Web of Conferences
This study investigates the potential of flavonoid compounds from Sandoricum koetjape leaf extracts as tyrosinase inhibitors, using in vitro and in silico methodologies.
Hamzah Fajar Nur   +8 more
doaj   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh   +5 more
wiley   +1 more source

The research on tyrosinase inhibition and biological activity of cinnamaldehyde and its derivatives [PDF]

open access: yes, 2016
酪氨酸酶(EC1.14.18.1)是一种含铜的氧化还原酶,广泛分布于微生物,动物,植物和人体中,是生物体生命活动的关键酶。若人体中酪氨酸酶异常表达能引起雀斑和黑色素沉积等皮肤病,且其在昆虫的蜕皮及果蔬褐变中起了关键的作用,因此酪氨酸酶抑制剂的研究引起了广泛的关注。肉桂醛主要存在于天然樟科植物桂皮中,在农业、医药上具有重要的作用。 本文首先以蘑菇酪氨酸酶为对象,研究了肉桂醛及其α位C上取代的三种衍生物:α-溴代肉桂醛、α-氯代肉桂醛和α-甲基肉桂醛对酶的抑制作用,结果表明四者抑制50%单酚酶活性的浓度 ...
崔沂
core  

Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico

open access: yesMolecules, 2018
Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and age
EunJin Bang   +11 more
doaj   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang   +7 more
wiley   +1 more source

Estudios de acoplamiento molecular de nuevos análogos de quinolonas a la ADN girasa de Escherichia coli [PDF]

open access: yes, 2018
Indexación: Scopus.Chemicals and CAS Registry Numbers: amino acid, 65072-01-7; ciprofloxacin, 85721-33-1; DNA topoisomerase (ATP hydrolysing); gatifloxacin, 112811-59-3, 180200-66-2; levofloxacin, 100986-85-4, 138199-71-0; lomefloxacin, 98079-51-7 ...
Davila, C.   +3 more
core  

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